156720-48-8

Basic information

• Product Name: 6,8-Dioxa-2-thiaspiro[3.5]nonane, 7,7-dimethyl-
• CAS NO: 156720-48-8
• Molecular Formula: C8H14O2S
• Molecular Weight: 174.264
• Mol File: 156720-48-8.mol

Chemical Properties

• CAS DataBase Reference: 6,8-Dioxa-2-thiaspiro[3.5]nonane, 7,7-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 6,8-Dioxa-2-thiaspiro[3.5]nonane, 7,7-dimethyl-(156720-48-8)
• EPA Substance Registry System: 6,8-Dioxa-2-thiaspiro[3.5]nonane, 7,7-dimethyl-(156720-48-8)

Safety Data

• Hazardous Substances Data: 156720-48-8(Hazardous Substances Data)

Upstream product

• 43153-20-4 5,5-bis-bromomethyl-2,2-dimethyl-[1,3]dioxane 
• 3296-90-0 bis(bromomethyl)bis(hydroxymethyl)methane 

Downstream Products

• 1431969-59-3 N-((5-(mercaptomethyl)-2,2-dimethyl-1,3-dioxan-5-yl)methyl)-2-(((5-(mercaptomethyl)-2,2-dimethyl-1,3-dioxan-5-yl)methyl)thio)-aniline 
• 1422688-42-3 N-((5-((benzylthio)methyl)-2,2-dimethyl-1,3-dioxan-5-yl)methyl)-2-(((5-((benzylthio)methyl)-2,2-dimethyl-1,3-dioxan-5-yl)methyl)thio)-aniline 
• 1335107-23-7 bis((5-((benzylthio)methyl)-2,2-dimethyl-1,3-dioxan-5-yl)methyl)sulfane 
• 1335107-33-9 C₅₁H₆₈N₄O₉S₄ 
• 1335107-45-3 (2,2,5-trimethyl-1,3-dioxan-5-yl)methyl 4-(3-(4-cyanophenyl)-5-(4-(3,3,13,13-tetramethyl-2,4,12,14-tetraoxa-8,17,23-trithia-20-azadispiro[5.3.5.9]tetracosan-20-yl)phenyl)-4,5-dihydro-1H-pyrazol-1-yl)-3,5-difluorobenzene-1-sulfonate 
• 1335107-44-2 (2,2,5-trimethyl-1,3-dioxan-5-yl)methyl 4-(3-(4-cyanophenyl)-5-(4-(3,3,13,13-tetramethyl-2,4,12,14-tetraoxa-8,17,23-trithia-20-azadispiro[5.3.5.9]tetracosan-20-yl)phenyl)-4,5-dihydro-1H-pyrazol-1-yl)-3-fluorobenzene-1-sulfonate 
• 1335107-43-1 (2,2,5-trimethyl-1,3-dioxan-5-yl)methyl 4-(3-(4-cyanophenyl)-5-(4-(3,3,13,13-tetramethyl-2,4,12,14-tetraoxa-8,17,23-trithia-20-azadispiro[5.3.5.9]tetracosan-20-yl)phenyl)-4,5-dihydro-1H-pyrazol-1-yl)benzene-1-sulfonate 
• 1335107-26-0 4-(3-(4-(3,3,13,13-tetramethyl-2,4,12,14-tetraoxa-8,17,23-trithia-20-azadispiro[5.3.5.9]tetracosan-20-yl)phenyl)prop-2-enoyl)benzonitrile 
• 1335107-25-9 4-(3,3,13,13-tetramethyl-2,4,12,14-tetraoxa-8,17,23-trithia-20-azadispiro[5.3.5.9]tetracosan-20-yl)benzaldehyde 
• 1335107-22-6 5-((benzylthio)methyl)-5-bromomethyl-2,2-dimethyl-1,3-dioxane 
• 959865-42-0 1-[3,3-bis[(benzoyloxy)methyl]thietan-2-yl]thymine 
• 183606-12-4 3,3-bis[(benzoyloxy)methyl]thietan-1-oxide 

Relevant articles and documents

Copper-Catalyzed Oxyalkynylation of C-S Bonds in Thiiranes and Thiethanes with Hypervalent Iodine Reagents

We report the oxyalkynylation of thiiranes and thietanes using ethynylbenziodoxolone reagents (EBXs) to readily access functionalized building blocks bearing an alkynyl, a benzoate, and an iodide group. The reaction proceeds with high atom efficiency most

Diverse ring opening of thietanes and other cyclic sulfides: An electrophilic aryne activation approach

Organosulfides are a common class of structure units in bioactive molecules and functional materials motivating continuous developments of efficient synthetic methods. Herein, we report an electrophilic aryne-activated ring opening protocol of one or two

Designed to dissolve: Suppression of colloidal aggregation of Cu(I)-selective fluorescent probes in aqueous buffer and in-gel detection of a metallochaperone

Due to the lipophilicity of the metal-ion receptor, previously reported Cu(I)-selective fluorescent probes form colloidal aggregates, as revealed by dynamic light scattering. To address this problem, we have developed a hydrophilic triarylpyrazoline-based fluorescent probe, CTAP-2, that dissolves directly in water and shows a rapid, reversible, and highly selective 65-fold fluorescence turn-on response to Cu(I) in aqueous solution. CTAP-2 proved to be sufficiently sensitive for direct in-gel detection of Cu(I) bound to the metallochaperone Atox1, demonstrating the potential for cation-selective fluorescent probes to serve as tools in metalloproteomics for identifying proteins with readily accessible metal-binding sites.

Synthesis of thietane nucleosides by glycosidation of thietanose derivatives with nucleobases

Thietane nucleosides were synthesized by the glycosidation of glycosyl fluoride with nucleobase.

Nucleosides and nucleotides. 159. Synthesis of thietane nucleosides via the Pummerer reaction as a key step

New thymine thietane nucleosides 7 and 20 were synthesized via Pummerer rearrangement of the corresponding sulfoxides 5 and 18 in the presence of thymine. TMSOTf, Et3N, and ZnI2 as a key step.