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1567334-76-2

2-[5-(4-chlorophenyl)-3-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-pyrazol-1-yl]pyridine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1567334-76-2 Structure

  • Basic information

    1. Product Name: 2-[5-(4-chlorophenyl)-3-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-pyrazol-1-yl]pyridine
    2. Synonyms:
    3. CAS NO:1567334-76-2
    4. Molecular Formula:
    5. Molecular Weight: 395.932
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1567334-76-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-[5-(4-chlorophenyl)-3-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-pyrazol-1-yl]pyridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-[5-(4-chlorophenyl)-3-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-pyrazol-1-yl]pyridine(1567334-76-2)
    11. EPA Substance Registry System: 2-[5-(4-chlorophenyl)-3-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-pyrazol-1-yl]pyridine(1567334-76-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1567334-76-2(Hazardous Substances Data)

1567334-76-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1567334-76-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,6,7,3,3 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1567334-76:
(9*1)+(8*5)+(7*6)+(6*7)+(5*3)+(4*3)+(3*4)+(2*7)+(1*6)=192
192 % 10 = 2
So 1567334-76-2 is a valid CAS Registry Number.

1567334-76-2Downstream Products

1567334-76-2Relevant articles and documents

Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain

Wall, Mark J.,Subasinghe, Nalin L.,Winters, Michael P.,Lubin, Mary Lou,Finley, Michael F.A.,Qin, Ning,Brandt, Michael R.,Neeper, Michael P.,Schneider, Craig R.,Colburn, Raymond W.,Flores, Christopher M.,Sui, Zhihua

, p. 3780 - 3783 (2018)

A novel series of pyrazolyltetrahydropyran N-type calcium channel blockers are described. Structural modifications of the series led to potent compounds in both a cell-based fluorescent calcium influx assay and a patch clamp electrophysiology assay. Representative compounds from the series were bioavailable and showed efficacy in the rat CFA and CCI models of inflammatory and neuropathic pain.

SUBSTITUTED PYRAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS

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Page/Page column 114; 115; 116, (2014/03/22)

The present invention relates to compounds of Formula (I), wherein X1, X2, X3, X4, R1, R2, R3, and Q are as defined herein, useful as N-type calcium channel blockers.

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