1567372-19-3

Upstream product

• 1567372-00-2 tert-butyl 3-(4-chlorophenyl)-2-(2-methoxyphenyl)-2,6-dihydropyrrolo[3,4-c]pyrazole-5(4H)-carboxylate 
• 1567373-46-9 t-butyl 3-bromo-2-(2-methoxyphenyl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate 
• 1586755-65-8 t-butyl (3-bromoprop-2-yn-1-yl)(2-chloro-2-(2-(2-methoxyphenyl)hydrazono)ethyl)carbamate 
• 1567373-44-7 t-butyl (3-bromoprop-2-yn-1-yl)(2-(2-(2-methoxyphenyl)hydrazinyl)-2-oxoethyl)carbamate 
• 1567373-43-6 2-((3-bromoprop-2-yn-1-yl)(t-butoxycarbonyl)amino)acetic acid 
• 158979-29-4 2-((tert-butoxycarbonyl)(prop-2-yn-1-yl)-amino)acetic acid 
• 10147-37-2 Isopropylsulfonyl chloride 

Relevant academic research and scientific papers

Discovery and SAR of novel tetrahydropyrrolo[3,4-c]pyrazoles as inhibitors of the N-type calcium channel

A novel series of substituted tetrahydropyrrolo[3,4-c]pyrazoles were investigated as blockers of the N-type calcium channel (Cav2.2 channels), a chronic pain target.

PYRROLOPYRAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS

Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: Formula. (I) wherein R1, R2 R3, Q, and G are defined herein.