15674-36-9

Upstream product

• 67-56-1 methanol 
• 129169-42-2 (2,2-dimethylpent-4-en-1-yl)benzene 
• 14248-22-7 methyl 2,2-dimethyl-3-phenylpropionate 
• 13351-61-6 2,2-dimethyl-3-phenyl-1-propanol 
• 13705-45-8 3,3-dimethyl-4-phenylbutanenitrile 

Downstream Products

• 1205639-26-4 (RS)-5-(2,2-dimethyl-3-phenyl-propyl)-imidazolidine-2,4-dione 
• 1280208-31-2 1-{4'-[4-(1-Hydroxy-3,3-dimethyl-4-phenyl-butyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester 

Relevant academic research and scientific papers

Metal-Free Enantioselective Oxidative Arylation of Alkenes: Hypervalent-Iodine-Promoted Oxidative C?C Bond Formation

The enantioselective oxyarylation of (E)-6-aryl-1-silyloxylhex-3-ene was achieved using a lactate-based chiral hypervalent iodine(III) reagent in the presence of boron trifluoride diethyl etherate. The silyl ether promotes the oxidative cyclization, and enhances the enantioselectivity. In addition, the corresponding aminoarylation was achieved.

Aromatic annulation with naphtho[1,8-de]-1,3-dithiin carbocations

The title carbocations have been produced by the reaction of silver trifluoromethanesulfonate with mixed orthothioesters. Intramolecular aromatic electrophilic substitution (annulation) of the cationic intermediates proceeds readily and provides an efficient, chemoselective route for appending six-membered rings to nonactivated aromatic systems.