156742-99-3Relevant articles and documents
Synthetic studies towards Chlorahololides A: practical synthesis of a lindenane-type sesquiterpenoid core framework with a 5,6-double bond
Liu, Yong,Nan, Fa-Jun
scheme or table, p. 1374 - 1376 (2010/05/19)
Towards Chlorahololides A: a lindenane-type sesquiterpenoid framework that contains a 5,6-double bond was synthesized from simple starting materials. The reductive cyclization of a 1,6-enyne and an unusual endo-type intramolecular Heck reaction was used as key steps for ring closure.
Synthesis of isopropenylcyclopropanes - Revision of the relative configuration of cyclopropyl ketones obtained by 1,3-elimination of γ-epoxy ketones
Cossy, Janine,Blanchard, Nicolas,Meyer, Christophe
, p. 339 - 348 (2007/10/03)
Efficient stereoselective routes towards isopropenylcyclopropanes have been devised. Secondary cis-isopropenylcyclopropylcarbinols have been obtained either by regio- and stereoselective hydroxy-directed cyclopropanation of the corresponding dienols or from bicyclic cyclopropyl lactones derived from intramolecular cyclopropanation of allylic diazoacetates. Contrary to previous reports, base-induced 1,3-elimination of γ-epoxy ketones has been shown to afford trans-2-(hydroxymethyl)cyclopropyl ketones, and the reactivity of these compounds has been reinvestigated.
Acidic Isomerization of Vicinally Substituted (cis)-Acceptor-Donor Cyclopropanes via an Open Ring Mechanism
Dechoux, Luc,Doris, Eric
, p. 2017 - 2020 (2007/10/02)
Many (cis)-cyclopropanes bearing 1-electronwithdrawing and 2-hydroxymethylene groups were synthesized under mild acidic conditions to afford the corresponding trans isomers.The mechanism is reported.
Diastereocontrol in the opening of vic-acceptor-donor cyclopropanes. Application to the synthesis of (cis) 1-EWG-2-hydroxymethylcyclopropanes
Dechoux, Luc,Doris, Eric,Jung, Louis,Stambach, Jean Francois
, p. 5633 - 5636 (2007/10/02)
Basic intramolecular ring opening reactions of vicinally substituted acceptor-donnor (trans)-cyclopropanes were studied. An application to the diastereoselective synthesis of (cis)-1-EWG-2-hydroxymethylcyclopropanes is presented.
A simple one-pot preparation of (Z)-cyclopropanes from γ,δ-ketoalkenes using KOH/DMSO intramolecular alkylation conditions
Dechoux, Luc,Ebel, Maurice,Jung, Louis,Stambach, Jean Francois
, p. 7405 - 7408 (2007/10/02)
Sequential treatment of λ,δ-ketoalkenes with aqueous NBS in DMSO and KOH as solid provides (Z)-cyclopropanes in good overall yields with a diastereoselective excess>;99%.
