156757-18-5

Basic information

• Product Name: 4-Piperidinethiol,1-(1-methylethyl)-(9CI)
• Synonyms: 4-Piperidinethiol,1-(1-methylethyl)-(9CI);4-Piperidinethiol
• CAS NO: 156757-18-5
• Molecular Formula: C₈H₁₇NS
• Molecular Weight: 159.29228
• Product Categories: ISOPROPYL
• Mol File: 156757-18-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 208.0±33.0 °C(Predicted)
• Appearance: /
• Density: 0.96±0.1 g/cm3(Predicted)
• PKA: 10.96±0.20(Predicted)
• CAS DataBase Reference: 4-Piperidinethiol,1-(1-methylethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinethiol,1-(1-methylethyl)-(9CI)(156757-18-5)
• EPA Substance Registry System: 4-Piperidinethiol,1-(1-methylethyl)-(9CI)(156757-18-5)

Safety Data

• Hazardous Substances Data: 156757-18-5(Hazardous Substances Data)

Upstream product

• 5355-68-0 1-Isopropyl-4-piperidone 

Relevant articles and documents

Novel 3-(4-piperidinylthio)-1H-indoles as potent nonopioid orally active central analgesics

A series of 3-(4-piperidinylthio)-1H-indoles was synthesized and evaluated in mice in the phenylbenzoquinone(PBQ)-induced writhing and hot plate tests. Most of these compounds are good analgesics with activities comparable to that of morphine. Among them compound 1i (UP 237-61), which has a strong serotonin binding profile, has an interesting antinociceptive activity which is not reserved by naloxone. (C) 2000 Elsevier Science Ltd. All rights reserved.

Piperidinylthioindole derivatives, their methods of preparation and pharmaceutical compositions in which they are present, useful especially as analgesics

The present invention relates to the derivatives of the formula STR1 and their addition salts, and to their use in therapeutics, especially as drugs having analgesic properties.