156766-85-7

Upstream product

• 156714-40-8 (2R,3S,4R,5S,6S,8R,9R,10R,11S,12S,13R)-8,8-(epoxymethano)-9,11-(S)-(ethylidenedioxy)-3,5-(isopropylidenedioxy)-2,4,6,10,12,13-hexamethyltetradecanolide 
• 156629-10-6 (2R,3S,4R,5S,6S,8R,9R,10R,11S,12S,13R)-9,11-(S)-(ethylidenedioxy)-8-hydroxy-8-(iodomethyl)-3,5-(isopropylidenedioxy)-2,4,6,10,12,13-hexamethyltetradecanolide 
• 156629-04-8 (2R,3S,4S,5S,6S,7E)-4,6-(R)-(ethylidenedioxy)-3,5-dimethyl-7-nonen-2-ol 
• 160796-76-9 (2R,3S,4R,5S,6S,9R,10R,11R,12R,13R)-3,5-<(p-bromobenzylidene)dioxy>-9,11-dihydroxy-2,4,6,10,12,13-hexamethyl-8-methylenetetradecanolide 
• 156629-06-0 (R)-2-Benzenesulfinyl-3-[(4R,5S,6R)-6-((S)-2-benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-1-{(2S,4R,5R,6S)-6-[(1S,2R)-2-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,5-dimethyl-[1,3]dioxan-4-yl}-butan-1-ol 
• 156629-09-3 (2R,3S,4R,5S,6S,9R,10R,11S,12S,13R)-9,11-(S)-(ethylidenedioxy)-3,5-(isopropylidenedioxy)-2,4,6,10,12,13-hexamethyl-8-oxotetradecanolide 
• 160691-52-1 (2R,3S,4R,5S,6S,9R,10R,11S,12S,13R)-9,11-(S)-(ethylidenedioxy)-3,5-(isopropylidenedioxy)-2,4,6,10,12,13-hexamethyl-8-methylenetetradecanolide 
• 160691-50-9 (2S,3R,4S,5R,6R)-O-benzyl-3,5-(isopropylidenedioxy)-2,4,6-trimethyl-7-(phenylthio)heptan-1-ol 
• 156629-02-6 (2R,3R,4S,5S,6R)-2,4-(S)-(ethylidenedioxy)-6-<(p-methoxybenzyl)oxy>-3,5-dimethylheptanal 
• 160691-47-4 (2E,4S,5S,6S,7S)-8-(benzyloxy)-4,6-(R)-(ethylidenedioxy)-5,7-dimethyl-2-octene 
• 160691-49-6 (2R,3R,4S,5S,6E)-3,5-(R)-(ethylidenedioxy)-2,4-dimethyl-6-octenal 
• 160691-48-5 (2S,3S,4S,5S,6E)-3,5-(R)-(ethylidenedioxy)-2,4-dimethyl-6-octen-1-ol 
• 160691-36-1 (2S,3S,4S,5R,6S)-7-(benzyloxy)-3,5-(isopropylidenedioxy)-2,4,6-trimethylheptyl p-toluenesulfonate 
• 160691-35-0 (2S,3S,4S,5R,6S)-7-(benzyloxy)-3,5-dihydroxy-2,4,6-trimethylheptyl p-toluenesulfonate 

Relevant academic research and scientific papers

Studies in macrolide synthesis: A stereocontrolled synthesis of oleandolide employing reagent- and substrate-controlled aldol reactions of (S)-1-(benzyloxy)-2-methylpentan-3-one

A highly stereocontrolled total synthesis of oleandolide (2), the aglycon of the macrolide antibiotic oleandomycin (1), has been completed in 8% overall yield (20 steps longest linear sequence, 26 steps in total) with 90% overall diastereoselectivity. Ini