160691-35-0

Basic information

• Product Name: (2S,3S,4S,5R,6S)-7-(benzyloxy)-3,5-dihydroxy-2,4,6-trimethylheptyl p-toluenesulfonate
• Synonyms: (2S,3S,4S,5R,6S)-7-(benzyloxy)-3,5-dihydroxy-2,4,6-trimethylheptyl p-toluenesulfonate
• CAS NO: 160691-35-0
• Molecular Weight: 450.596
• Mol File: 160691-35-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2S,3S,4S,5R,6S)-7-(benzyloxy)-3,5-dihydroxy-2,4,6-trimethylheptyl p-toluenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,4S,5R,6S)-7-(benzyloxy)-3,5-dihydroxy-2,4,6-trimethylheptyl p-toluenesulfonate(160691-35-0)
• EPA Substance Registry System: (2S,3S,4S,5R,6S)-7-(benzyloxy)-3,5-dihydroxy-2,4,6-trimethylheptyl p-toluenesulfonate(160691-35-0)

Safety Data

• Hazardous Substances Data: 160691-35-0(Hazardous Substances Data)

Upstream product

• 116652-76-7 Weinreb amide of (S)-3-benzyloxy-2-methylpropionic acid 
• 116661-41-7 (2S,4R,5R)-1-(benzyloxy)-5-hydroxy-2,4,6-trimethylhept-6-en-3-one 
• 116546-78-2 (S)-1-benzyloxy-2-methylpentan-3-one 
• 74924-27-9 methyl (S)-3-benzyloxy-2-methylpropanoate 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 140925-44-6 (2S,3S,4R,5R,6S)-7-(benzyloxy)-2,4,6-trimethyl-1,3,5-heptanetriol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 160691-36-1 (2S,3S,4S,5R,6S)-7-(benzyloxy)-3,5-(isopropylidenedioxy)-2,4,6-trimethylheptyl p-toluenesulfonate 
• 141566-34-9 (2R,5S,6R,7S,8S,9R)-3-Benzenesulfinyl-9-benzyloxymethoxy-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-2-[(4R,5S,6R)-6-((S)-2-hydroxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-6,8-dimethyl-decan-4-ol 
• 141566-35-0 (R)-2-{(4S,5R,6S)-6-[(1S,4S,5R,6S,7S,8R)-8-Benzyloxymethoxy-4,6-bis-(tert-butyl-dimethyl-silanyloxy)-1,5,7-trimethyl-3-oxo-nonyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-propionic acid 
• 156629-06-0 (R)-2-Benzenesulfinyl-3-[(4R,5S,6R)-6-((S)-2-benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-1-{(2S,4R,5R,6S)-6-[(1S,2R)-2-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,5-dimethyl-[1,3]dioxan-4-yl}-butan-1-ol 
• 156766-85-7 (2R,3S,4R,5S,6S,8S,10R,11R,12R,13R)-3,5-<(p-bromobenzylidene)dioxy>-8,8-(epoxymethano)-11-hydroxy-2,4,6,10,12,13-hexamethyl-9-oxotetradecanolide 
• 156766-84-6 (2R,3S,4R,5S,6S,8S,9R,10R,11R,12R,13R)-3,5-<(p-bromobenzylidene)dioxy>-8,8-(epoxymethano)-9,11-dihydroxy-2,4,6,10,12,13-hexamethyltetradecanolide 
• 160691-50-9 (2S,3R,4S,5R,6R)-O-benzyl-3,5-(isopropylidenedioxy)-2,4,6-trimethyl-7-(phenylthio)heptan-1-ol 
• 160691-42-9 C₄₁H₆₉Cl₃O₉Si₂ 
• 86534-97-6 (2S,3S,4S,5R,6S)-7-hydroxy-3,5-(isopropylidenedioxy)-2,4,6-trimethylheptyl p-toluenesulfonate 
• 86534-98-7 (SRS,2S,3R,4S,5R,6R)-3,5-(isopropylidenedioxy)-2,4,6-trimethyl-7-(phenylsulfinyl)heptan-1-ol 
• 160691-37-2 (2S,3R,4S,5R,6R)-3,5-(isopropylidenedioxy)-2,4,6-trimethyl-7-(phenylthio)heptan-1-ol 

Relevant articles and documents

Studies in macrolide synthesis: A stereocontrolled synthesis of oleandolide employing reagent- and substrate-controlled aldol reactions of (S)-1-(benzyloxy)-2-methylpentan-3-one

A highly stereocontrolled total synthesis of oleandolide (2), the aglycon of the macrolide antibiotic oleandomycin (1), has been completed in 8% overall yield (20 steps longest linear sequence, 26 steps in total) with 90% overall diastereoselectivity. Ini

Studies in macrolide synthesis: A stereocontrolled synthesis of a (9S)-macrolide intermediate for oleandomycin using chiral boron reagents

The (9S)-macrolide 1 (P = TBS) was prepared in 14 stpes (5% yield) with 63% overall ds starting from the ethyl ketone (S)-2. The C1-C7 and C8-C13 segments, 3 and 4, were obtained via boron enolate aldol reaction