156768-68-2

Upstream product

• 130874-90-7 4,5-dimethyl (4R,5R)-2-(4-methoxyphenyl)-1,3-dioxolane-4,5-dicarboxylate 

Downstream Products

• 156696-24-1 (2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-2-butanol 
• 156696-20-7 (2S,3S)-2-(4-methoxybenzyloxy)-3,4-O-(3-pentylidene)-1,3,4-butanetriol 
• 156696-22-9 (2S,3S)-3-[(4-methoxybenzyl)oxy]butane-1,2,4-triol 
• 184839-79-0 C₃₃H₃₆O₆ 
• 184839-78-9 Methanesulfonic acid (1S,2S)-3-benzyloxy-1-benzyloxymethyl-2-(4-methoxy-benzyloxy)-propyl ester 
• 184839-77-8 (2S,3S)-1,4-Bis-benzyloxy-3-(4-methoxy-benzyloxy)-butan-2-ol 
• 180153-88-2 (S)-3-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-(4-methoxy-benzyloxy)-ethyl]-1-trimethylsilanyl-hexa-1,5-diyn-3-ol 
• 180153-86-0 (S)-5-(tert-Butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyloxy)-1-trimethylsilanyl-pent-1-yn-3-one 
• 180153-84-8 (2S,3S)-4-(tert-Butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-butane-1,2-diol 
• 220271-25-0 (4S,5S)-4,5-diethynyl-2-(4-methoxyphenyl)-1,3-dioxolane 
• 184839-76-7 (4S,5S)-4,5-Bis-benzyloxymethyl-2-(4-methoxy-phenyl)-[1,3]dioxolane 
• 156696-23-0 (2S,3S)-1,4-bis(tert-butyldimethylsilyloxy)-2,3-O-(4-methoxybenzylidene)-2,3-butanediol 

Relevant academic research and scientific papers

Efficient synthesis of a carbocyclic core moiety with the stereochemistry of the C-1027 chromophore

A stereoselective and concise route to the bicyclo[7.3.0]dodecadiyne core moiety (26) of the C-1027 chromophore (1) through highly efficient LiN(TMS)2/CeCl3-mediated cyclization of alkynyl aldehyde 24 has been established.

A PROCESS FOR THE PREPARATION OF TREOSULFAN

The present invention relates to a process for the preparation of Treosulfan using sodium borohydride and iodine as reducing agent, which is less hazardous and convenient as compared to the reagents used in the prior art. The invention also relates to a novel intermediate to obtain Treosulfan in high yield and high purity.

Large laboratory scale synthesis of (2S,3S)-2-(4-methoxybenzyloxy)-3,4-O- (3-pentylidene)-1,3,4-butantriol, a versatile chiral building block in natural product synthesis

(2S,3S)-2-(4-Methoxybenzyloxy)-3,4-O-(3-pentylidene)-1,3,4-butanetriol (3), a versatile chiral building block for an essential structural unit of complex natural products, was synthesized starting from dimethyl L-(+)- tartrate (5) on both a small scale and a large scale in good yield.