156782-56-8Relevant articles and documents
Neuroprotective 3,4-dihydro-2(1H)-quinolone compounds
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, (2008/06/13)
The present invention is directed to compounds of formula (I), and the pharmaceutically acceptable acid addition salts thereof, wherein R is selected from the group consisting of F,--CF3, --OCH3, --O(C1)alkyl substituted with 1 to 3 fluoro atoms. --O(C2) substituted with 1 to 5 fluoro atoms, and --O(C3)alkyl substituted with 1 to 7 fluoro atoms. The compounds of formula (I) are useful in the treatment of stroke, traumatic brain injury and central nervous system degenerative diseases.