50329-87-8

Usage

Uses

Used in Pharmaceutical Industry:
4-(4-Methoxy-phenyl)-piperidin-4-ol is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and properties make it a promising candidate for the development of drugs targeting specific medical conditions.
Used in Drug Development:
4-(4-Methoxy-phenyl)-piperidin-4-ol is used as a key component in the formulation of new drugs. Its potential pharmaceutical applications include the treatment of neurological disorders, pain management, and other therapeutic areas. Researchers are actively exploring its potential and optimizing its properties for maximum efficacy and safety in drug development.

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 3612-20-2 1-phenylmethyl-4-piperidone 

Downstream Products

• 49798-08-5 5-{2-[4-hydroxy-4-(4-methoxy-phenyl)-piperidin-1-yl]-ethyl}-oxazolidin-2-one 
• 71916-55-7 4-(4-methoxyphenyl)-4-hydroxy-1-[4-[[7-(trifluoromethyl)-4-quinolinyl]amino]benzoyl]piperidine 
• 88780-60-3 4-Hydroxy-4-(4-methoxy-phenyl)-piperidine-1-carbaldehyde 
• 137884-24-3 4-(4-Hydroxyphenyl)-1-{3-(4-morpholinyl)propyl}-1,2,5,6-tetrahydropyridine 
• 1021171-34-5 C₂₀H₃₀N₂O₄ 
• 156782-56-8 6-[2S*-(4-Hydroxy-4-(4-methoxyphenyl)piperidino)-1S*-hydroxypropyl]-3, 4-dihydro-2(1H)-quinolone mesylate 
• 21820-70-2 5-{2-[4-hydroxy-4-(4-methoxy-phenyl)-piperidin-1-yl]-ethyl}-3-methyl-oxazolidin-2-one 

Relevant academic research and scientific papers

Drug Repurposing of Haloperidol: Discovery of New Benzocyclane Derivatives as Potent Antifungal Agents against Cryptococcosis and Candidiasis

Despite the high morbidity and mortality of invasive fungal infections (IFIs), effective and safe antifungal agents are rather limited. Starting from antifungal lead compound haloperidol that was identified by drug repurposing, a series of novel benzocycl

Benzo aliphatic ring derivatives, and applications thereof

The invention discloses benzo aliphatic ring derivatives, and applications thereof. The benzo aliphatic ring derivatives are prepared through substation of benzo aliphatic ring compounds with nitrogenheterocyclic ring containing substituent groups. Most o

Studies on the N-dealkylated metabolite of haloperidol

The recent detection of 4-Chlorophenyl-4-piperidinol (CPPO), in rats fed haloperidol and the subsequent demonstration that CPPO produces a freezing action in frogs, has encouraged us to study the structural features that might be responsible for the freezing action. In this study, we have shown that removal of the chloro from the phenyl ring has little effect on the freezing action and the removal of the tertiary alcohol from the piperidine only decreases somewhat the effectiveness of the freezing action. In addition, since replacing the piperidine ring with tetrahydropyridine and piperazine moieties led to compounds without the freezing action, and because 4-phenylpiperidine is the common entity in all the compounds with the freezing action, it is reasonable to suggest that the 4-phenylpiperidine moiety may be responsible for the freezing action observed in CPPO.

2-Piperidinoalkyl-1,4-benzodioxans

2-Piperidinoalkyl-1,4-benzodioxans, e.g. those of the formula STR1 AND ACID ADDITION SALTS THEREOF ARE NEUROLEPTIC AGENTS.

Neuroleptic 2-piperidinoalkyl-1,4-benzodioxans

2-Piperidinoalkyl-1,4-benzodioxans, e.g. those of the formula STR1 and acid addition salts thereof are neuroleptic agents.

2-Piperidinoalkyl-1,4-benzodioxans

2-Piperidinoalkyl-1,4 benzodioxans, e.g. those of the formula STR1 AND ACID ADDITION SALTS THEREOF ARE NEUROLEPTIC AGENTS.