1567820-77-2

Upstream product

• 1567820-72-7 (S)-3-(benzylamino)-2-hydroxy-3-oxopropyl 4-toluenesulfonate 
• 205122-64-1 (S)-N-benzyl 2,3-dihydroxypropionamide 
• 13304-62-6 N-benzylacrylamide 
• 1567820-75-0 (S)-N-benzyl-2-hydroxy-3-methoxypropanamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 100-46-9 benzylamine 

Downstream Products

• 474534-78-6 (S)-N-benzyl-2-amino-3-methoxypropionamide 
• 175481-36-4 lacosamide 
• 196601-69-1 (R)-2-amino-N-benzyl-3-methoxypropanamide 

Relevant academic research and scientific papers

IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE AND ITS NOVEL INTERMEDIATE

An improved, cost effective process for the preparation of Lacosamide is disclosed. A novel intermediate of formula (IV) and a process for preparation of the novel intermediate is also disclosed. wherein, X is halogen.

A non-infringing route for enantioselective synthesis of antiepileptic agent lacosamide

A non-infringing route for enantioselective synthesis of lacosamide has been developed. The synthesis started from commercially available acrylic acid and was completed in eight steps using Sharpless asymmetric dihydroxylation as a key step with an overal