15679-09-1

Usage

Uses

Used in Food Industry:
2-Ethylthiazole is used as a flavoring agent for its ability to impart savory and meat-like flavors to various food products, enhancing their taste profiles.
Used in Food Science Research:
It serves as a potential marker for Maillard reaction products in food, which is crucial for understanding and controlling the complex chemical reactions that occur during cooking and food processing.
Used in Pharmaceutical Industry:
2-Ethylthiazole is utilized in the synthesis of pharmaceuticals and other organic compounds, contributing to the development of new drugs and medicinal agents.
Used in Antimicrobial and Antifungal Applications:
Its potential antimicrobial and antifungal properties are being studied for use in various applications, including as a preservative in food products or in the development of new treatments for microbial infections.

InChI:InChI=1/C5H7NS/c1-2-5-6-3-4-7-5/h3-4H,2H2,1H3

Upstream product

• 108284-82-8 2-ethyl-2,5-dihydro-thiazole 
• 631-58-3 thiopropanamide 
• 17157-48-1 bromoacetaldehyde 
• 74-96-4 ethyl bromide 
• 69749-91-3 2-(methanesulfonyl)thiazole 
• 593-60-2 Vinyl bromide 
• 120258-27-7 2-ethyl-4-bromothiazole 
• 209260-74-2 2-vinyl-4-bromothiazole 
• 3581-87-1 2-methylthiazole 
• 74-88-4 methyl iodide 

Downstream Products

• 19968-50-4 ethyl-2 phenyl-4 thiazole 
• 19968-74-2 2-ethyl-5-phenyl-thiazole 
• 933683-87-5 2-ethylthiazole-5-carbaldehyde 
• 3292-77-1 2-bromo-1-thiazol-2-yl-ethanone 
• 1311412-52-8 C₂₉H₃₃FN₂O₄S 
• 24295-03-2 2-Acetylthiazole 

Relevant academic research and scientific papers

Preparation method of 2-alkyl substituted thiazole compound

The invention discloses a preparation method of a 2-alkyl substituted thiazole compound, which comprises the following steps: oxidizing 2-alkyl thiothiazole into 2-alkyl sulfonyl thiazole, mixing the 2-alkyl sulfonyl thiazole with a Grignard reagent, reacting the mixture at 0-5 DEG C, heating the mixture to room temperature to continue the reaction; then adding an acid solution and continuously reacting the components at room temperature to obtain a 2-alkyl substituted thiazole compound, wherein the structural formula of the 2-alkyl thiothiazole is that a Grignard reagent of the 2-alkyl sulfonyl thiazole is RCH2MgX, R1 is selected from C1-C4 alkyl groups, R is selected from H and C1-C4 alkyl groups, and X is halogen. According to the present invention, the use of the expensive palladium catalyst and the ligand is avoided, the use of the poor safety butyl lithium reagent is avoided, the ultra-low temperature of-78 DEG C is not required, the cheap and easily available 2-alkylthiothiazole is adopted as the starting material, the 2-alkyl substituted thiazole compound can be prepared under the milder condition, and the method is suitable for the industrial production.

Epothilone analogs

Novel analogs of epothilone A, epothilone B, and epothilone C are synthesized by Stille coupling thazole-stannanes to macrolactone intermediates. The synthetic epothilone analogs selectively prevent mitosis in cancer cells through the induction and stabilization of microtubulin assembly. Selected synthetic epothilone analogs are demonstrated to have greater bioactivity than their corresponding native compound.

Pharmaceutical compositions and methods of inhibiting gastric acid secretion

Pharmaceutical compositions and methods of inhibiting gastric acid secretion by administering N-alkenyl and N-alkynyl thioamides.