15679-11-5Relevant academic research and scientific papers
Synthesis of 2-imino-4-thiazolines, 2-imino-4-alkoxythiazolidines, thiazoles and 4-imidazolin-2-ones from α-halomethyl ketimines
De Kimpe, Norbert,De Cock, Wim,Keppens, Marian,De Smaele, Dirk,Meszaros, Andrea
, p. 1179 - 1183 (1996)
A variety of heterocycles, including 3,4-disubstituted-2-imino-4-thiazolines, 3,4-disubstituted-4-methoxy-2-iminothiazolidines, 2,4-disubstituted-thiazoles, 2-amino-4-substituted-thiazoles and 1,5-disubstituted-4-imidazolin-2-ones, were synthesized from α-chloromethyl and α-bromomethyl ketimines by condensation with potassium thiocyanate, thiourea, ammonium thiocyanate and potassium cyanate.
Synthesis of thiazoles and aminothiazoles from β-keto tosylates under supramolecular catalysis in the presence of β-cyclodextrin in water
Kumar, V. Pavan,Narender,Sridhar,Nageswar,Rao, K. Rama
, p. 4331 - 4336 (2008/03/13)
This is the first report on the supramolecular synthesis of thiazoles/aminothiazoles from β-keto tosylates and thioamide/thiourea in water in the presence of β-cyclodextrin in impressive yields. Formation of inclusion complexes was explained from 1H NMR studies. Copyright Taylor & Francis Group, LLC.
