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3,3-dimethyl-1-(tosyloxy)butan-2-one is an organic compound with the molecular formula C12H18O4S. It is a colorless to pale yellow liquid with a molecular weight of 262.33 g/mol. 3,3-dimethyl-1-(tosyloxy)butan-2-one is characterized by the presence of a butan-2-one (ketone) group, two methyl groups attached to the third carbon, and a tosyloxy (tosylate) group attached to the first carbon. The tosyloxy group is derived from toluene, with a sulfonyl group (-SO2-) attached to the para position of the benzene ring. 3,3-dimethyl-1-(tosyloxy)butan-2-one is used as a synthetic intermediate in the preparation of various organic compounds, particularly in the synthesis of pharmaceuticals and agrochemicals. It is also known for its potential applications in the field of asymmetric catalysis. Due to its reactivity and functional groups, it is essential to handle 3,3-dimethyl-1-(tosyloxy)butan-2-one with care, as it may be sensitive to moisture and heat.

7257-96-7

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7257-96-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7257-96-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,5 and 7 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 7257-96:
(6*7)+(5*2)+(4*5)+(3*7)+(2*9)+(1*6)=117
117 % 10 = 7
So 7257-96-7 is a valid CAS Registry Number.

7257-96-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,3-dimethyl-1-(tosyloxy)butan-2-one

1.2 Other means of identification

Product number -
Other names 3,3-dimethyl-1-(toluene-4-sulfonyloxy)-butan-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7257-96-7 SDS

7257-96-7Relevant academic research and scientific papers

α-Tosyloxylation of fluorosubstituted β-diketones

Ratner, V. G.,Pashkevich, K. I.

, p. 501 - 502 (2007/10/02)

The interaction of fluorinated β/diketones with benzene leads to α-tosyloxy-β-diketones existing in the form of stable hydrates. - Key words: fluorosubstituted β-diketones; α-tosyloxylation; de(perfluoroacyl)ation.

Triphenylbismuthonium 2-Oxoalkylide, A Moderately Stabilized Bismuthonium Ylide: Generation and Reactions with Some Electrophiles

Matano, Yoshihiro

, p. 2703 - 2710 (2007/10/02)

Treatment of (2-oxoalkyl)triphenylbismuthonium tetrafluoroborates 3 with potassium tert-butoxide in tetrahydrofuran at -78 deg C produced triphenylbismuthonium 2-oxoalkylides 4, which readily underwent epoxidation with the aldehydes 5 to give the α,β-epoxy ketones 7 with highly trans selectivity.The ylide 4a reacted with dimedone 11, the sulfonic acid 13, the thiol 15 and the isocyanate 17 to afford the corresponding ketones 12, 14, 16 and 19 in moderate to good yields.Reaction of the ylide 4c with the α,β-unsaturated ketones 10 and 21 afforded the 1,2-dibenzoyl- and the 1,2,3-tribenzoyl- cyclopropanes 20 and 22, respectively, although the yields were low.In the presence of a catalytic amount of nitrosobenzene 23, the ylide 4a a unique decomposition to give the 2,2,7,7-tetramethyloct-4-ene-3,6-dione 24 in quantitative yield, while the reaction with the nitrile oxide 25 yielded the isoxazoline 26.In all of these reactions, triphenylbusmuthane 6 was the additional major product.

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