1567951-64-7Relevant articles and documents
Synthesis of 3,4-diaryl- and 4-acyl-3-arylpyrroles and study of their antimitotic activity
Samet,Sil’yanova,Ushkarov,Semenova,Semenov
, p. 858 - 865 (2018/08/28)
The Barton–Zard reaction of nitro substituted stilbenes and chalcones with ethyl isocyanoacetate afforded 3,4-diaryl- and 4-acyl-3-arylpyrroles, respectively. 3-Arylpyrrole-2,4- dicarboxylates and 4-arylisoxazoline N-oxides were side reaction products. An
A copper-catalyzed coupling reaction of vinyl halides and carbazates: Application in the assembly of polysubstituted pyrroles
Zhou, Chengang,Ma, Dawei
supporting information, p. 3085 - 3088 (2014/03/21)
CuI-catalyzed coupling of vinyl halides with carbazates gives N-protected N-alkenylhydrazines, which are condensed with ketones under acidic conditions to give polysubstituted pyrroles. The pyrrole synthesis may go through a similar mechanism with Fischer indole synthesis, which involves a [3,3]-sigmatropic rearrangement and other reactions. The Royal Society of Chemistry.