156810-04-7Relevant articles and documents
COMPOUNDS INTERACTING WITH THE NEUROEXCITATORY AMINO ACIDS: SYNTHESIS OF 2-(4-ARALKYLPIPERAZINE-1-YL)-1-ARYLETHANOLS
Silhankova, Alexandra,Dobrovsky, Karel,Krejci, Ivan,Polivka, Zdenek
, p. 658 - 666 (1994)
Amino ketones Ia - If and III were synthesized.Their reduction gave corresponding alcohols IIa - IIf, IVa and IVb.These were evaluated by methods of biochemical and behavioural pharmacology.
Discovery of phenylpiperazine derivatives as IGF-1R inhibitor with potent antiproliferative properties in vitro
Guo, Feng-Jiao,Sun, Juan,Gao, Li-Li,Wang, Xin-Yi,Zhang, Yang,Qian, Shao-Song,Zhu, Hai-Liang
, p. 1073 - 1077 (2015/02/19)
A series of phenylpiperazine derivatives (3a-3q) were designed and synthesized. In vitro assays indicated that several phenylpiperazine derivatives had excellent antiproliferative properties against four cancer cell lines including multidrug-resistant can