156881-63-9

Usage

Chemical Properties

White Powder

InChI:InChI=1/C12H21NO4/c1-12(2,3)17-11(16)13(8-10(14)15)9-6-4-5-7-9/h9H,4-8H2,1-3H3,(H,14,15)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 2521-86-0 (2R)-cyclopentyl glycine 
• 188347-99-1 ((R)-1-Cyclopentyl-2-hydroxy-ethyl)-carbamic acid tert-butyl ester 

Downstream Products

• 161253-78-7 (S)-2-{(R)-2-[((S)-1-{(R)-2-[(R)-2-Benzyloxycarbonylamino-3-(2-methyl-1H-indol-3-yl)-propionylamino]-3-methoxycarbonyl-propionyl}-pyrrolidine-2-carbonyl)-amino]-2-cyclopentyl-acetylamino}-4-methyl-pentanoic acid benzyl ester 
• 161253-77-6 (S)-2-((R)-2-{[(S)-1-((R)-2-tert-Butoxycarbonylamino-3-methoxycarbonyl-propionyl)-pyrrolidine-2-carbonyl]-amino}-2-cyclopentyl-acetylamino)-4-methyl-pentanoic acid benzyl ester 
• 177914-12-4 (S)-2-({(R)-[((S)-Benzyloxycarbonyl-cyclopropyl-methyl)-carbamoyl]-cyclopentyl-methyl}-carbamoyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 161253-84-5 (S)-2-{[(R)-((S)-1-Benzyloxycarbonyl-3-methyl-butylcarbamoyl)-cyclopentyl-methyl]-carbamoyl}-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1026598-40-2 (S)-2-((R)-2-Amino-2-cyclopentyl-acetylamino)-4-methyl-pentanoic acid benzyl ester 
• 177914-10-2 (S)-((R)-2-tert-Butoxycarbonylamino-2-cyclopentyl-acetylamino)-cyclopropyl-acetic acid benzyl ester 
• 177914-20-4 (S)-2-((R)-2-tert-Butoxycarbonylamino-2-cyclopentyl-acetylamino)-4-methyl-pentanoic acid benzyl ester 

Relevant academic research and scientific papers

Chiral electrophilic 'glycinal' equivalents. New synthons for optically active α-amino acids and 4-substituted 2-oxazolidinones

The thermal reaction of 3-[(1S)-2-alkoxy-1-apocamphanecarbonyl]-2-oxazolones (21a-c) with dialkyl azodicarboxylates (9) results in exclusive formation of [4 + 2] type cycloadducts (22 and 23) with moderate levels of diastereofacial selection (up to 72% d.e.). The diastereomers thus obtained were readily purified and subsequent treatment with acidic methanol followed by removal of the auxiliary with LiBH4/MeOH (1:2) gave optically pure 4-methoxy-5-hydrazino-2-oxazolidinones (26 and 27), which serve as α-aminoaldehyde templates useful for the synthesis of a wide variety of optically active α-amino acids as well as 4-alkyl and 4-aryl-2-oxazolidinones.

Bradykinin receptor antagonists containing N-substituted amino acids: In vitro and in vivo B2 and B1 receptor antagonist activity

We report a systematic probing of the structural requirements of the bradykinin (BK) type 2 (B2) receptor for antagonist activity by incorporating N-alkyl-amino acid residues at positions 7 and 8 of a potent antagonist sequence. Compound 1 (D-A