156892-82-9

Usage

Uses

Used in Pharmaceutical Industry:
Benzyl N-(2-amino-2-methylpropyl)carbamate is used as an antimicrobial agent for its broad-spectrum activity against various bacteria, including carbapenem-resistant strains. It is particularly useful for treating bacterial infections caused by multidrug-resistant pathogens, offering a potential solution to the growing problem of antibiotic resistance.
Used in Research and Development:
Benzyl N-(2-amino-2-methylpropyl)carbamate is used as a candidate for further research and development in the field of antimicrobial therapy. Its unique chemical structure and properties make it a valuable subject for studying new approaches to combat bacterial infections and developing novel antibiotics.

Upstream product

• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 811-93-8 1,1-dimethylethylenediamine 
• 28170-07-2 benzyl phenyl carbonate 
• 100-51-6 benzyl alcohol 
• 31139-36-3 dibenzyl dicarbonate 
• 1885-14-9 phenyl chloroformate 
• 169954-67-0 (2-benzyloxycarbonylamino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester 

Downstream Products

• 169954-67-0 (2-benzyloxycarbonylamino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester 
• 851726-78-8 benzyl 2-(ethylamino)-2-methylpropylcarbamate 

Relevant academic research and scientific papers

Tricyclic compound, pharmaceutical composition and application thereof

The present invention provides a tricyclic compound, an isomer thereof, a pharmaceutically acceptable salt, a pharmaceutical composition and an application thereof. The tricyclic compound has a structure represented by formula I, has a significant effect of inhibiting RET kinase activity, can effectively inhibit cancer cell proliferation, can be used as an RET kinase inhibitor, can be used for preparing medicines for treating RET kinase-mediated diseases, has a good treatment effect on RET kinase-mediated cancers and other diseases, and has a wide application prospect.

allah Geleg sandbank method for the preparation of intermediates

The invention relates to a preparation method of Anagliptin intermediates (2-amino-2-methyl-propyl)-benzyl carbamate and (2-amino-1, 1-dimethyl-ethyl)-tert-butyl carbamate, wherein the preparation method is short in reaction period, simple to operate, eas

Inducing achiral aliphatic oligoureas to fold into helical conformations

The ability of urea-linked oligomers of achiral diamines (achiral analogues of the well-established chiral oligourea foldamers) to adopt helical conformations was explored spectroscopically. Up to four achiral units were ligated either to a well-formed helical trimer or to a single chiral diamine, and the extent to which they adopted a screw-sense preference was determined by NMR and CD. In the best performing cases, a trimeric chiral oligourea and even a single cis-cyclohexanediamine monomer induced folding into a helical conformation.

NOVEL CONJUGATES OF CC-1065 ANALOGS AND BIFUNCTIONAL LINKERS

This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multipl

HYDROXY PYRIDOPYRROLOPYRAZINE DIONE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS

Hydroxy-substituted pyridopyrrolopyrazine dione compounds are inhibitors of HIV integrase and inhibitors of HIV replication. In one embodiment, the dione compounds are of Formula (I): (I) wherein a, b, A, B, R1, R2, R3, R4, R5, R6, R7 and R8 are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

Selective synthesis of carbamate protected polyamines using alkyl phenyl carbonates

Utilising alkyl phenyl carbonates, an economical, practical and versatile method for selective Boc, Cbz and Alloc protection of polyamines has been developed. This method allows Boc, Cbz and Alloc protection of primary amines in the presence of secondary amines by reaction of the polyamines with the alkyl phenyl carbonates. Also, this method allows mono carbamate protection of simple symmetrical aliphatic α,ω-alkanediamines in high yields with respect to the diamine. Finally, the method allows selective carbamate protection of a primary amine located on a primary carbon in the presence of a primary amine located on a secondary or a tertiary carbon in excellent yields.

Substituted dibenzoxazepine and dibenzthiazepine carbamate compounds, pharmaceutical compositions and methods of use

The present invention provides substituted dibenzoxazepine and dibenzthiazepine compounds of Formula I: STR1 which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a com

Substituted dibenzoxazepine and dibenzthiazepine urea compounds, pharmaceutical compositions and methods of use

The present invention provides substituted dibenzoxazepine and dibenzthiazepine compounds of Formula I: STR1 which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a com