156892-82-9

Basic information

• Product Name: benzyl N-(2-aMino-2-Methylpropyl)carbaMate
• Synonyms: benzyl N-(2-aMino-2-Methylpropyl)carbaMate;Benzyl 2-aMino-2-MethylpropylcarbaMate;(2-Amino-2-methyl-propyl)-carbamic acid benzyl ester;2-Methyl-2-amino-N-Cbz-propanamine
• CAS NO: 156892-82-9
• Molecular Formula: C₁₂H₁₈N₂O₂
• Molecular Weight: 222.28352
• Mol File: 156892-82-9.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: benzyl N-(2-aMino-2-Methylpropyl)carbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl N-(2-aMino-2-Methylpropyl)carbaMate(156892-82-9)
• EPA Substance Registry System: benzyl N-(2-aMino-2-Methylpropyl)carbaMate(156892-82-9)

Safety Data

• Hazardous Substances Data: 156892-82-9(Hazardous Substances Data)

Usage

General Description

Benzyl N-(2-amino-2-methylpropyl)carbamate, also known as Carbapenem-1, is a synthetic chemical compound with potential therapeutic applications. It is a carbamate derivative containing a benzyl group, an amino group, and a carbapenem core. benzyl N-(2-aMino-2-Methylpropyl)carbaMate has been studied for its antimicrobial properties and potential use as an antibiotic. It is known for its broad-spectrum activity against a variety of bacteria, including carbapenem-resistant strains. Benzyl N-(2-amino-2-methylpropyl)carbamate shows promise as a potential treatment for bacterial infections, especially those caused by multidrug-resistant pathogens. Its chemical structure and properties make it a promising candidate for further research and development in the field of antimicrobial therapy.

Upstream product

• 28170-07-2 benzyl phenyl carbonate 
• 811-93-8 1,1-dimethylethylenediamine 
• 169954-67-0 (2-benzyloxycarbonylamino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester 
• 1885-14-9 phenyl chloroformate 
• 31139-36-3 dibenzyl dicarbonate 
• 100-51-6 benzyl alcohol 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 

Downstream Products

• 851726-78-8 benzyl 2-(ethylamino)-2-methylpropylcarbamate 
• 169954-67-0 (2-benzyloxycarbonylamino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Tricyclic compound, pharmaceutical composition and application thereof

The present invention provides a tricyclic compound, an isomer thereof, a pharmaceutically acceptable salt, a pharmaceutical composition and an application thereof. The tricyclic compound has a structure represented by formula I, has a significant effect of inhibiting RET kinase activity, can effectively inhibit cancer cell proliferation, can be used as an RET kinase inhibitor, can be used for preparing medicines for treating RET kinase-mediated diseases, has a good treatment effect on RET kinase-mediated cancers and other diseases, and has a wide application prospect.

Inducing achiral aliphatic oligoureas to fold into helical conformations

The ability of urea-linked oligomers of achiral diamines (achiral analogues of the well-established chiral oligourea foldamers) to adopt helical conformations was explored spectroscopically. Up to four achiral units were ligated either to a well-formed helical trimer or to a single chiral diamine, and the extent to which they adopted a screw-sense preference was determined by NMR and CD. In the best performing cases, a trimeric chiral oligourea and even a single cis-cyclohexanediamine monomer induced folding into a helical conformation.

MONO carbamate protection of aliphatic diamines using alkyl phenyl carbonates [(2-Aminoethyl)carbamic acid tert-butyl ester]

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