156897-01-7

Upstream product

• 20850-49-1 2-(3,4-dimethoxyphenyl)-3-methylbutyronitrile 
• 156896-99-0 2-(3,4-dimethoxyphenyl)-2-formyl-3-methylbutanenitrile 
• 156896-98-9 ethyl-2-(3,4-dimethoxyphenyl)-2-cyano-3-methylbutanoate 
• 156897-00-6 2-(3,4-dimethoxyphenyl)-2-isopropyl-4,4-dibromo-3-butenenitrile 

Downstream Products

• 156896-80-9 5-[(5,6-Dimethoxy-indan-2-yl)-methyl-amino]-2-(3,4-dimethoxy-phenyl)-2-isopropyl-pent-3-ynenitrile 
• 156896-78-5 2-(3,4-Dimethoxy-phenyl)-5-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino}-2-isopropyl-pent-3-ynenitrile 

Relevant academic research and scientific papers

Synthesis and pharmacological evaluation of verapamil analogs with restricted molecular flexibility

Several analogs of verapamil, which are characterized by a reduced molecular flexibility, have been synthesized.Their pharmacological activity has been evaluated on guinea-pig atria (negative chronotropic and inotropic activities) and guinea-pig aorta str