156905-81-6

Basic information

• Product Name: 8-Acetoxymethyl-4-benzyloxy-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,2,6-tricarboxylic acid 6-tert-butyl ester 1,2-dimethyl ester
• Synonyms: 8-Acetoxymethyl-4-benzyloxy-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,2,6-tricarboxylic acid 6-tert-butyl ester 1,2-dimethyl ester
• CAS NO: 156905-81-6
• Molecular Weight: 552.581
• Mol File: 156905-81-6.mol

Chemical Properties

• CAS DataBase Reference: 8-Acetoxymethyl-4-benzyloxy-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,2,6-tricarboxylic acid 6-tert-butyl ester 1,2-dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Acetoxymethyl-4-benzyloxy-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,2,6-tricarboxylic acid 6-tert-butyl ester 1,2-dimethyl ester(156905-81-6)
• EPA Substance Registry System: 8-Acetoxymethyl-4-benzyloxy-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,2,6-tricarboxylic acid 6-tert-butyl ester 1,2-dimethyl ester(156905-81-6)

Safety Data

• Hazardous Substances Data: 156905-81-6(Hazardous Substances Data)

Upstream product

• 762-42-5 dimethyl acetylenedicarboxylate 
• 132628-60-5 3-acetoxymethyl-5-amino-6-benzyloxy-1-t-butoxycarbonyl-2,3-dihydro-1H-indole 

Downstream Products

• 156905-83-8 4-Benzyloxy-8-chloromethyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,2,6-tricarboxylic acid 6-tert-butyl ester 1,2-dimethyl ester 
• 156905-82-7 4-Benzyloxy-8-hydroxymethyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,2,6-tricarboxylic acid 6-tert-butyl ester 1,2-dimethyl ester 

Relevant articles and documents

Synthesis and antitumor activity of novel cyclopropapyrroloindole (CPI) derivatives bearing bis(methoxycarbonyl) groups

The title synthesis was achieved by employing oxidative cyclization of the enaminodiester prepared by Michael addition of the 5-aminoindoline with dimethyl acetylenedicarboxylate, as a key step. Some of these novel bis(methoxycarbonyl)cyclopropapynroloindole (MC2CPI) derivatives 9c, d and their seco-chlorides 18c, d were found to exhibit prominent cytotoxicity and antitumor activity against P388 murine leukemia.