1569075-93-9

Upstream product

• 1569075-92-8 ethyl 2-((1S,2S,5S,6S)-2-((benzylthio)carbonyl)-2,6-dimethyl-5-((triisopropylsilyl)oxy)cyclohexyl)acetate 
• 1549824-53-4 (1S,2S,3S,4S)-phenyl-2-(2-ethoxy-2-oxoethyl)-1,3-dimethyl-4-(triisopropylsilyloxy)cyclohexanecarboxylate 

Downstream Products

• 1569075-99-5 ethyl 2-{(1S,2R,5S,6S)-2-[(E)-6-iodo-3,3-dimethoxyhepta-1,6-dien-1-yl]-2,6-dimethyl-5-triisopropylsilyloxycyclohexyl}acetate 
• 1569076-00-1 C₂₈H₅₃IO₄Si 
• 1569076-02-3 2-{(1S,2R,5S,6S)-2-[(E)-6-iodo-3,3-dimethoxyhepta-1,6-dien-1-yl]-2,6-dimethyl-5-triisopropylsilyloxycyclohexyl}acetaldehyde 
• 1569076-05-6 (4aR,4bS,7S,8S,8aS,10aR)-4b,8-dimethyl-10a-phenylthiomethyl-7-triisopropylsilyloxydecahydrophenanthrene-3,10(2H,4H)-dione 
• 1569076-06-7 (4aS,4bS,7S,8S,8aS,10aS)-4b,8-dimethyl-10a-phenylthiomethyl-7-triisopropylsilyloxydecahydrophenanthrene-3,10(2H,4H)-dione 
• 1569075-96-2 C₂₆H₄₉IO₃Si 
• 1569075-97-3 C₂₆H₄₅IO₃Si 
• 1569075-95-1 ethyl 2-{(1S,2R,5S,6S)-2-[(E)-6-iodo-3-oxohepta-1,6-dien-1-yl]-2,6-dimethyl-5-triisopropylsilyloxycyclohexyl}acetate 

Relevant academic research and scientific papers

Research on Liebeskind-Srogl coupling/intramolecular Diels-Alder reaction cascade

The Liebeskind-Srogl coupling/intramolecular Diels-Alder (IMDA) reaction cascade that stereoselectively affords a tricarbocyclic compound with a trans–trans-cis fused ring system including an all-carbon quaternary stereogenic center at the ring junction is described. The cascade reactions proceed quickly and stereoselectively afford the products within 2 h at room temperature in the presence of a suitable thioester. The developed protocol as well as the prepared chiral compounds are useful for the enantioselective total synthesis of terpenoids with the trans–trans-cis fused ring system.

Stereoselective construction of the ABC-ring system of fusidane triterpenes via intermolecular/transannular Michael reaction cascade

A stereoselective construction of the ABC-ring system of fusidane triterpenes via intermolecular/transannular Michael reaction cascade is described. The substrate, a ten-membered carbocyclic ketone, has been successfully prepared by the Cr-mediated intramolecular alkenylation of the corresponding acyclic compound. The array of functionalities in the product stereoselectively obtained by the cascade reaction is useful for further structural modifications directed toward the total synthesis of fusidane and other triterpenes, and designed molecules intended for studying structure-activity relationships.