156924-92-4

Basic information

• Product Name: (3S,4S)-(E)-(3-tert-butoxycarbonylamino)-4-methyl-1-phenyl-1-hexene
• Synonyms: (3S,4S)-(E)-(3-tert-butoxycarbonylamino)-4-methyl-1-phenyl-1-hexene
• CAS NO: 156924-92-4
• Molecular Weight: 289.418
• Mol File: 156924-92-4.mol

Chemical Properties

• CAS DataBase Reference: (3S,4S)-(E)-(3-tert-butoxycarbonylamino)-4-methyl-1-phenyl-1-hexene(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4S)-(E)-(3-tert-butoxycarbonylamino)-4-methyl-1-phenyl-1-hexene(156924-92-4)
• EPA Substance Registry System: (3S,4S)-(E)-(3-tert-butoxycarbonylamino)-4-methyl-1-phenyl-1-hexene(156924-92-4)

Safety Data

• Hazardous Substances Data: 156924-92-4(Hazardous Substances Data)

Upstream product

• 1080-32-6 O,O-diethyl benzylphosphonate 
• 118171-79-2 N-(t-butoxycarbonyl)-isoleucine aldehyde 
• 13139-16-7 N-(tert-butyloxycarbonyl)-L-isoleucine 
• 87694-51-7 N-(tert-butoxycarbonyl)-L-isoleucine N'-methoxy-N'-methylamide 
• 1449-46-3 benzyltriphenylphosphonium bromide 

Downstream Products

• 405115-75-5 (S)-2-[(1S,2S)-2-Methyl-1-((E)-styryl)-butylcarbamoyl]-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Discovery and parallel synthesis of a new class of cathepsin K inhibitors

Peptidomimetic aminomethyl ketones have been identified as a new class of cathepsin K inhibitors. Traditional and high-speed parallel synthesis techniques were applied to investigate this series. Structure-activity relationships were established, and certain analogues were characterized with IC50 values in the range 200-500 nM.

PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST

Short-chain peptide derivatives acting on angiotensin IV receptor at low concentrations. Because of agonistically acting on angiotensin IV receptor, the novel peptide derivatives of the present invention represented by the following formula (1) are useful as remedies for various diseases in which angiotensin IV participates: