1569303-97-4

Basic information

• Product Name: 1-phenyl-5-(3,4,5-trimethoxyphenylthio)-1H-tetrazole
• CAS NO: 1569303-97-4
• Molecular Weight: 344.394
• Mol File: 1569303-97-4.mol

Chemical Properties

• CAS DataBase Reference: 1-phenyl-5-(3,4,5-trimethoxyphenylthio)-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-5-(3,4,5-trimethoxyphenylthio)-1H-tetrazole(1569303-97-4)
• EPA Substance Registry System: 1-phenyl-5-(3,4,5-trimethoxyphenylthio)-1H-tetrazole(1569303-97-4)

Safety Data

• Hazardous Substances Data: 1569303-97-4(Hazardous Substances Data)

Upstream product

• 86-93-1 1-Phenyl-1H-tetrazole-5-thiol 
• 1569303-99-6 3,4,5-trimethoxyphenylzinc bromide 
• 53724-68-8 1-phenyl-5-tetrazolyl sulfenyl chlorides 

Relevant articles and documents

AROMATIC SULFIDE COMPOUNDS AND METHODS AND USE THEREOF

Described herein, inter alia, are aromatic sulfide compositions and methods for treating or preventing cancer using the same.

Diaryl and heteroaryl sulfides: Synthesis via sulfenyl chlorides and evaluation as selective anti-breast-cancer agents

A mild protocol for the synthesis of diaryl and heteroaryl sulfides is described. In a one-pot procedure, thiols are converted to sulfenyl chlorides and reacted with arylzinc reagents. This method tolerates functional groups including aryl fluorides and chlorides, ketones, as well as N-heterocycles including pyrimidines, imidazoles, tetrazoles, and oxadiazoles. Two compounds synthesized by this method exhibited selective activity against the MCF-7 breast cancer cell line in the micromolar range.