53724-68-8Relevant articles and documents
Diaryl and heteroaryl sulfides: Synthesis via sulfenyl chlorides and evaluation as selective anti-breast-cancer agents
Yonova, Ivelina M.,Osborne, Charlotte A.,Morrissette, Naomi S.,Jarvo, Elizabeth R.
, p. 1947 - 1953 (2014/04/03)
A mild protocol for the synthesis of diaryl and heteroaryl sulfides is described. In a one-pot procedure, thiols are converted to sulfenyl chlorides and reacted with arylzinc reagents. This method tolerates functional groups including aryl fluorides and chlorides, ketones, as well as N-heterocycles including pyrimidines, imidazoles, tetrazoles, and oxadiazoles. Two compounds synthesized by this method exhibited selective activity against the MCF-7 breast cancer cell line in the micromolar range.
Reactions of 2,2-dimethyl-3-ethylidenenorbornane with sulfur-containing reagents
Lodochnikova,Nikitina,Plemenkov,Kataeva,Litvinov,Appolonova
, p. 229 - 233 (2007/10/03)
Addition of sulfur-containing reagents (thiols and sulfenyl chlorides) to 2,2-dimethyl-3-ethylidenenorbornane occurs by electrophilic mechanism regiospecifically at the terminal, sterically the most accessible allene multiple bond. The electrophilic moiet
REACTIONS OF 3,3-DISUBSTITUTED CYCLOPROPENES AND OTHER CYCLOOLEFINS WITH 1-PHENYLTETRAZOLE-5-SULFENYL CHLORIDE
Khaliullin, R. R.,Plemenkov, V. V.
, p. 612 - 615 (2007/10/02)
Reactions of 1-phenyltetrazole-5-sulfenyl chloride with 3,3-disubstituted cyclopropenes, cycloalkenes, and 3-carene give rise to 2-chloro-1-(1-phenyltetrazolylthio)cycloalkanes.The stereoselectivity of the addition of a heteryl sulfenyl chloride to unsymm
