156942-84-6

Basic information

• Product Name: 3H-1,2,4-Triazole-3-thione, 4-amino-2,4-dihydro-5-(4-iodophenyl)-
• CAS NO: 156942-84-6
• Molecular Formula: C8H7IN4S
• Molecular Weight: 318.141
• Mol File: 156942-84-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3H-1,2,4-Triazole-3-thione, 4-amino-2,4-dihydro-5-(4-iodophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-1,2,4-Triazole-3-thione, 4-amino-2,4-dihydro-5-(4-iodophenyl)-(156942-84-6)
• EPA Substance Registry System: 3H-1,2,4-Triazole-3-thione, 4-amino-2,4-dihydro-5-(4-iodophenyl)-(156942-84-6)

Safety Data

• Hazardous Substances Data: 156942-84-6(Hazardous Substances Data)

Upstream product

• 39115-95-2 4-iodobenzohydrazide 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 619-58-9 4-iodobenzoic acid 
• 75-15-0 carbon disulfide 

Downstream Products

• 1227682-12-3 C₂₈H₁₄I₂N₈S₂ 
• 1122552-49-1 2,5-bis[3-(p-iodophenyl)-1,2,4-triazolo[3,4-b]-[1,3,4]thiadiazol-6-yl]thiophene 
• 1119751-55-1 1,8-bis[(3-p-iodophenyl)-s-triazolo[3,4-b]-[1,3,4]thiadiazole-6-yl]octane 
• 1085384-90-2 C₂₅H₂₂I₂N₈S₂ 
• 1085387-68-3 C₂₃H₁₈I₂N₈S₂ 

Relevant articles and documents

Synthesis and biological evaluation of novel glycosyl-containing 1,2,4-triazolo[3,4-b][1,3,4]thiadiazole derivatives as acetylcholinesterase inhibitors

An efficient protocol for the synthesis of novel glycosyl-containing 1,2,4-triazolo[3,4-b][1,3,4]thiadiazole derivatives starting from the commercially available d-glucosamine hydrochloride is described by reaction of glycosyl isothiocyanate with various aminotriazoles in DMF. Glycosyl isothiocyanate is an important intermediate and synthetic methods are discussed. The acetylcholinesterase inhibitory activity of these compounds was tested by Ellman’s method. It was found that most compounds exhibited over 90% inhibition and they were subsequently evaluated for their IC50values.