1570075-93-2

Upstream product

• 1569649-68-8 5-bromo-1-isopropyl-6-methyl-4-oxo-1,4-dihydro-pyridine-3-carboxylic acid 
• 1570080-82-8 [[4-(aminomethyl)phenyl]-methyl-oxo-λ⁶-sulfanylidene]cyanamide 
• 83171-39-5 4-(methylthio)benzylamine 
• 247569-44-4 2-(4-methylthiobenzyl)isoindol-1,3-dione 
• 1570082-20-0 [[4-[(1,3-dioxoisoindolin-2-yl)methyl]phenyl]-methyl-λ⁴-sulfanylidene]cyanamide 
• 1570082-23-3 [[4-[(1,3-dioxoisoindolin-2-yl)methyl]phenyl]-methyl-oxo-λ⁶-sulfanylidene]cyanamide 
• 1541148-98-4 1-isopropyl-6-methyl-4-oxo-1,4-dihydro-pyridine-3-carboxylic acid 
• 33821-61-3 (E/Z)-3-((dimethylamino)methylene)-6-methyl-2H-pyran-2,4(3H)-dione 
• 854690-87-2 (3-(difluoromethyl)phenyl)boronic acid 
• 1570077-28-9 5-bromo-1-isopropyl-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid 4-(N-cyano-S-(methyl)sulfonimidoyl)benzylamide 

Downstream Products

• 1570075-95-4 5-(3-(difluoromethyl)phenyl)-1-isopropyl-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid 4-(N-cyano-S-(methyl)sulfonimidoyl)benzylamide 
• 1570075-94-3 5-(3-(difluoromethyl)phenyl)-1-isopropyl-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid 4-(N-cyano-S-(methyl)sulfonimidoyl)benzylamide 

Relevant academic research and scientific papers

SUBSTITUTED 4-PYRIDONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY

This invention relates to substituted 4-pyridones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other auto-immune and allergic disorders, allograft rejection, and oncological diseases.

SUBSTITUTED 4-PYRIDONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY

This invention relates to substituted 4-pyridones of formula (1) and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other auto-immune and allergic disorders, allograft rejection, and oncological diseases.