15701-82-3Relevant academic research and scientific papers
The first Corey-Chaykovsky epoxidation and cyclopropanation in ionic liquids
Chandrasekhar,Narasihmulu,Jagadeshwar,Reddy, K. Venkatram
, p. 3629 - 3630 (2003)
The first Corey-Chaykovsky epoxidation and cyclopropanation using trimethyl sulfonium iodide/trimethyl sulfoxonium iodide and KOH as base in the recyclable ionic liquid, (bmim)PF6 are described.
Facile synthesis of libraries of functionalized cyclopropanes and oxiranes using ionic liquids – A new approach to the classical Corey-Chaykovsky reaction
Malunavar, Shruti S.,Sutar, Suraj M.,Prabhala, Pavankumar,Savanur, Hemantkumar M.,Kalkhambkar, Rajesh G.,Aridoss, Gopalakrishnan,Laali, Kenneth K.
supporting information, (2021/09/13)
The potential of [PAIM][NTf2]/BMIM-ILs as a base/solvent in the Corey-Chaykovsky reaction is demonstrated by the facile synthesis of libraries of functionalized cyclopropanes from enones and oxiranes from aldehydes and ketones, at room temperature in respectable isolated yields. To demonstrate their application, the synthesized epoxides were employed as substrates for the synthesis of a library of 2,3-disubstituted quinolines, using [BMIM(SO3H)][OTf]/[BMIM][PF6] as a catalyst/solvent. The potential for recycling/reuse of the IL solvents was also explored.
EPOXIDE FORMATION FROM ALDEHYDES AND KETONES - A MODIFIED METHOD FOR PREPARING THE COREY-CHAYKOVSKY REAGENTS
Ng, John S.
, p. 1193 - 1202 (2007/10/02)
Trimethylsulfoxonium iodide and potassium tert-butoxide in dimethyl sulfoxide (DMSO) is a very efficient process for the multikilogram scale preparation of epoxides from aldehydes and ketones.
