157022-93-0Relevant academic research and scientific papers
Synthesis of Androst-5-en-7-ones and Androsta-3,5-dien-7-ones and Their Related 7-Deoxy Analogs as Conformational and Catalytic Probes for the Active Site of Aromatase
Numazawa, Mitsuteru,Mutsumi, Ayako,Tachibana, Mii,Hoshi, Kumiko
, p. 2198 - 2205 (1994)
A series of androst-5-en-7-ones and androsta-3,5-dien-7-ones and their 7-deoxy derivatives, respectively, were synthesized and tested for their abilities to inhibit aromatase in human placental microsomes.All the steroids inhibited the enzyme in a competi
