Journal of Medicinal Chemistry p. 2198 - 2205 (1994)
Update date:2022-09-26
Topics:
Numazawa, Mitsuteru
Mutsumi, Ayako
Tachibana, Mii
Hoshi, Kumiko
A series of androst-5-en-7-ones and androsta-3,5-dien-7-ones and their 7-deoxy derivatives, respectively, were synthesized and tested for their abilities to inhibit aromatase in human placental microsomes.All the steroids inhibited the enzyme in a competi
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