1570262-22-4

Upstream product

• 188355-96-6 5-nitro-[1,1'-biphenyl]-3-carboxylic acid 
• 117342-20-8 (3-(methoxycarbonyl)-5-nitrophenyl)boronic acid 
• 108-86-1 bromobenzene 
• 1570262-20-2 morpholino-(5-nitro-[1,1'-biphenyl]-3-yl)methanone 
• 941294-19-5 (3-bromo-5-nitrophenyl)(morpholin-4-yl)methanone 
• 6307-83-1 3-bromo-5-nitro-benzoic acid 

Downstream Products

• 1570255-74-1 morpholin-4-yl(5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}biphenyl-3-yl)methanone 

Relevant academic research and scientific papers

Kinase inhibitors (by machine translation)

The present invention relates to certain 4 - (substituted anilino) -2 - (substituted piperi -1 -yl) pyrimidine -5 - carboxamide compounds useful for the treatment or prevention of diseases or medical conditions mediated by signal transduction of CaMMK1 isotype. For example, such compounds and salts thereof may be used to treat or prevent a variety of different cancers. Diseases (including 2 diabetes) and/or immune-mediated diseases. (by machine translation)

SUBSTITUTED PHENYL SPLEEN TYROSINE KINASE (Syk) INHIBITORS

The invention provides certain substituted phenyl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, Rcy, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).