157061-99-9Relevant academic research and scientific papers
A highly selective and efficient access to N-9 alkylated purine derivatives via radical S(RN)1 chemistry
Gharbaoui,Benhida,Lechevallier,Maillos,Beugelmans
, p. 1161 - 1168 (1994)
6-Chloropurine and 2-amino-6-chloropurine were discovered to be efficient nucleophiles in S(RN)1 reactions with various gem halonitroalkane derivatives as substrates to give high yield of N-9 alkylated purine derivatives in a N- 9/N-7 ratio greater than 9
