1571105-08-2Relevant academic research and scientific papers
Knoevenagel Condensation of Phosphinoylacetic Acids with Aldehydes: An Efficient One-Pot Strategy for the Synthesis of P-Functionalized Alkenyl Compounds
Dziuba, Kamil,Frynas, S?awomir,Szwaczko, Katarzyna
, p. 2142 - 2154 (2021/01/21)
A wide range of commercially available aldehydes have been applied to Knoevenagel condensation reaction to give E -alkenylphosphine oxides and vinylphosphine oxides. The readily available phosphinoylacetic acids derived from P(O)-H compounds were used as the starting materials in the reaction, providing a highly stereoselective and efficient method for constructing α,β-unsaturated phosphine oxides. Moreover, this simple and practical procedure provides an alternative and more environmentally friendly synthesis strategy for this type of P-functionalized alkenyl compounds.
Copper-catalyzed synthesis of 1,3-butadienylphosphine oxides and chemoselective phosphoryl reduction to stereodefined 1,3-butadienylphosphines
Gatignol, Jérémie,Alayrac, Carole,Lohier, Jean-Fran?ois,Ballester, Jorge,Taillefer, Marc,Gaumont, Annie-Claude
supporting information, p. 2822 - 2826 (2014/03/21)
Copper-catalyzed CP cross-coupling reactions between diphenylphosphine oxide and various 1-bromo-1,3-butadienes readily provided a set of functionalized 1,3-butadienyldiphenylphosphine oxides. Application of the latter to the synthesis of stereodefined 1,3-butadienyldiphenylphosphines was successfully achieved via chemoselective reduction of their phosphoryl moiety.
