157117-32-3

Upstream product

• 142144-24-9 (2S,3S,4S,5S,6S)-2,4,6-trimethyl-8-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,5-di-tert-butylsilylenedioxyoctanal 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 157117-31-2 (5R,6S,7S,8S,9S,10S)-7,9-(di-tert-butylsilylenedioxy)-5-hydroxy-3-methylene-6,8,10-trimethyl-12-((2S',4R',6S')-2-methyl-4-methoxytetrahydropyran-6-yl)-dodecane 

Downstream Products

• 157117-37-8 (E,E,7S)-methyl-8-<(2R,6S)-6-<(2S,3R,4S,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-methoxy-4,6-((R)-para-methoxybenzylidenedioxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-1-yl>-5,6-dihydro-2H-... 
• 157117-36-7 (E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,4S,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-4,6-((R)-para-methoxybenzylidenedioxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-1-yl>-5,6-dihydro-2H-... 
• 169131-28-6 (E,E,7S)-methyl-8-<(2R,6S)-6-<(3R,4S,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-4,6-((R)-para-methoxybenzylidenedioxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-2-oxo-3,7,9,11-tetramethyltridecan-1-yl>-5,6-dihydro-2H-pyran-2-yl>-. 
• 157117-35-6 (E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,4S,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2,4-dihydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-1-yl>-5,6-dihydro-2H-pyran-2-yl>-... 
• 157117-34-5 (E,E,7S)-methyl-8-<(2R,6S)-6-<(2R,3R,6R,7S,8S,9S,10S,11S)-8,10-di-tert-butylsilylenedioxy-2-hydroxy-6-(para-methoxybenzyloxy)-13-((2S,4R,6S)-2-methyl-4-methoxytetrahydropyran-6-yl)-3,7,9,11-tetramethyltridecan-4-one-1-yl>-5,6-dihydro-2H-pyran-2-yl>-7-.. 

Relevant academic research and scientific papers

The Total Synthesis of Swinholide A. Part 3: A Stereocontrolled Synthesis of (-)-Pre-Swinholide A.

Two coupling strategies for (-)-pre-swinholide A were devised based on the analysis in Scheme 1.In the first route, a boron-mediated aldol reaction between the ethyl ketone 19 and the aldehyde 3 was used to construct the C15-C16 bond with moderate diaster