157143-20-9

Upstream product

• 57295-30-4 3-hydroxy-4-methylbenzaldehyde 
• 75-03-6 ethyl iodide 

Downstream Products

• 1067717-87-6 2-[1-(3-ethoxy-4-methyl-benzyl)-piperidin-4-yl]-2,3-dihydro-isoindol-1-one 
• 1084925-74-5 8-(3-ethoxy-4-methyl-benzyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione 
• 1084926-27-1 N-[4-cyano-1-(3-ethoxy-4-methyl-benzyl)-piperidin-4-yl]-5-methyl-nicotinamide 
• 1092464-59-9 [1-(3-ethoxy-4-methyl-benzyl)-piperidin-4-yl]-(3-phenyl-[1,2,4]oxadiazol-5-yl)-amine 
• 1245834-07-4 C₂₃H₃₁N₃O₂ 

Relevant academic research and scientific papers

PYRIMIDINE AND QUINAZOLINE DERIVATIVES

This invention is concerned with compounds of the formula ( l ) wherein A, R1 to R5 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

PYRIDINE, QUINOLINE AND PYRIMIDINE DERIVATIVES

This invention is concerned with compounds of the formula wherein A, R1 to R5 are as defined in the specification and G is a pyridine, quinoline or pyrimidine group as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

BENZOIMIDAZOLE, TETRAHYDRO-QUINOXALINE, BENZOTRIAZOLE, DIHYDRO-IMIDAZO[4,5-c] PYRIDINONE AND DIHYDRO-ISOINDOLONE DERIVATIVES

This invention relates to compounds of the formula wherein A, R1 to R3 are as defined in the specification and G is benzoimidazole, quinoxaline, benzotriazole, dihydro-imidazo[4,5-c]pyridine and dihydro-isoindolone group as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES

This invention relates to 4,4-disubstituted piperidine derivatives of the formula wherein A and R1 to R5 are as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceuti

Pyrimidine, quinazoline, pteridine and triazine derivatives

This invention is concerned with compounds of the formula wherein A, R1 to R5 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES

This invention is concerned with compounds of the formula (I) wherein X, A, B, R1, R2 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical

Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives

This invention is concerned with compounds of the formula wherein A, B1, B2, R1, R2 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

Compositions containing aromatic aldehydes and their use in treatments

Disclosed are pharmaceutical and cosmetic compositions containing aromatic aldehyde compounds. Some of the disclosed compositions are useful as topical therapeutics for treating inflammatory dermatologic conditions. Some of the compositions are useful in transdermal and other systemic dose forms for treating other inflammatory conditions in mammals.

3-Alkoxy Substituted Oligo- and Poly(1,4-phenyleneethenylene)s

The 3-alkoxy-4-methylbenzaldehydes (3a-e) can be obtained by alkylation of the hydroxy compound 1.Reaction with aniline yields the azomethines (4a-e) which enter in an alkaline medium a polycondensation to the title compounds 5a-e.Contrary to the 2-substituted educts, a competitive intramolecular condensation process is principally not possible.Benzoylation of 1 furnisches 3f.However, the corresponding Schiff base 4 f is not capable of a condensation reaction because the ester group is cleaved.