15724-79-5Relevant articles and documents
Efficient synthesis of β-chlorovinylketones from acetylene in chloroaluminate ionic liquids
Snelders, Dennis J. M.,Dyson, Paul J.
supporting information; experimental part, p. 4048 - 4051 (2011/10/04)
A method for the Friedel-Crafts-type insertion reaction of acetylene with acid chlorides in chloroaluminate ionic liquids is presented. The use of ionic liquids not only serves to avoid the use of carbon tetrachloride or 1,2-dichloroethane but also suppresses side reactions, notably the polymerization of acetylene, which occurs in these chlorinated solvents. Consequently, the products can be isolated using a simpler purification procedure, giving a range of aromatic and aliphatic β-chlorovinyl ketones in high yield and purity.
A Route from 1,1,1,3-Tetrachloro-3-phenylpropane to Ethynyl Phenyl Ketone Involving Elimination of Hydrogen Chloride and 1,3-Proton Transfer
Akiyama, Takeo,Yoshida, Yasuki,Hanawa, Tokiko,Sugimori, Akira
, p. 1795 - 1798 (2007/10/02)
The treatment of 1,1,1,3-tetrachloro-3-phenylpropane with alkali in ethanol affords ethynyl phenyl ketone and its acetal in good yields.This reaction proceeds through the elimination of hydrogen chloride and an efficient 1,3-proton transfer catalyzed by base.Ethyl cinnamate is obtained in only 2percent yield.
