157251-21-3

Basic information

• Product Name: Phosphonic acid, [[(triphenylphosphoranylidene)amino]methyl]-, diethyl ester
• CAS NO: 157251-21-3
• Molecular Formula: C23H27NO3P2
• Molecular Weight: 427.42
• Mol File: 157251-21-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [[(triphenylphosphoranylidene)amino]methyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [[(triphenylphosphoranylidene)amino]methyl]-, diethyl ester(157251-21-3)
• EPA Substance Registry System: Phosphonic acid, [[(triphenylphosphoranylidene)amino]methyl]-, diethyl ester(157251-21-3)

Safety Data

• Hazardous Substances Data: 157251-21-3(Hazardous Substances Data)

Upstream product

• 124316-00-3 1-<<(Triphenylphosphoranylidene)amino>methyl>benzotriazole 
• 762-04-9 phosphonic acid diethyl ester 
• 3084-40-0 diethyl (1-hydroxymethyl)phosphonate 
• 17982-55-7 diethyl (azidomethyl)phosphonate 
• 603-35-0 triphenylphosphine 

Downstream Products

• 26067-99-2 1,1,4,4-tetraphenyl-2-aza-1,3-butadiene 
• 64244-33-3 [1-Phenyl-meth-(E)-ylidene]-((E)-styryl)-amine 
• 125877-36-3 1,4-diphenyl-2-aza-1,3-butadiene 
• 882883-77-4 1,4-bis-(4-methoxyphenyl)-2-aza-1,3-butadiene 
• 20495-33-4 diethyl N-benzoyl-α-aminomethylphosphonate 
• 119-65-3 isoquinoline 

Relevant articles and documents

Synthesis and antiproliferative activity of novel α- And β-dialkoxyphosphoryl isothiocyanates

A series of 15 mostly new dialkoxyphosphoryl alkyl and aralkyl isothiocyanates were synthesized using two alternative strategies, and their in vitro antiproliferative activity against several cancer cell lines (including drug resistant) is here demonstrat

Synthesis of amidines derived from phosphonates and phosphane oxides - Amidine-mediated preparation of phosphorylated oxazolines

Alkylation of N-(phosphorylalkyl)phosphazenes 2 with methyl iodide and allyl bromide and acylation with ethyl chloroformate leads to the formation of aminophosphonium salts 4 derived from (aminoalkyl)phosphonates. N-(Phosphorylalkyl)amidines 8 were obtained by reaction of phosphazenes derived from aminophosphonates with benzoyl chloride and subsequent addition of amines. These functionalized amidines were used as key intermediates in the synthesis of oxazolin-4-ylphosphonates 9 and 10. In a similar manner, oxazolin-4-ylphosphane oxides 17 and 18 were prepared from N-(phosphanylalkyl)amidines 16, which were obtained by reaction of phosphazenes derived from phosphane oxides 15 with benzoyl chloride and amines. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.

1,2- and 1,3-Monoazabisylides as Novel Synthons

The 1,2- and 1,3-monoazabisylides (5 and 11, respectively) were prepared in situ by the reactions of 1-methyl>benzotriazole (betmip, 2) with diethyl phosphite anion and methylenetriphenylphosphorane, respectively, followed by treatment with butyllithium.The synthetic versatility of the new reagents 5 and 11 is illustrated by convenient methods for the preparation of isoquinoline, 2-azabutadienes, 2,3-diarylpyrroles, and 2-(3H)-benzazepine.