1572529-59-9

Basic information

• Product Name: 2-chloro-β-methyl-N-phenyl-benzene ethanamine
• Synonyms: 2-chloro-β-methyl-N-phenyl-benzene ethanamine
• CAS NO: 1572529-59-9
• Molecular Weight: 245.752
• Mol File: 1572529-59-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-chloro-β-methyl-N-phenyl-benzene ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-β-methyl-N-phenyl-benzene ethanamine(1572529-59-9)
• EPA Substance Registry System: 2-chloro-β-methyl-N-phenyl-benzene ethanamine(1572529-59-9)

Safety Data

• Hazardous Substances Data: 1572529-59-9(Hazardous Substances Data)

Upstream product

• 2039-87-4 2-chlorostyrene 
• 100-61-8 N-methylaniline 
• 89-98-5 2-chloro-benzaldehyde 
• 62-53-3 aniline 

Relevant articles and documents

Two-Step Procedure for the Synthesis of 1,2,3,4-Tetrahydro-quinolines

A new two-step procedure that includes an initial regioselective intermolecular hydroaminoalkylation of ortho-chlorostyrenes with N-methylanilines and a subsequent intramolecular Buchwald–Hartwig amination gives direct access to 1,2,3,4-tetrahydroquinolines. The hydroaminoalkylation reaction of the ortho-chlorostyrenes is catalyzed by a 2,6-bis(phenylamino)pyridinato titanium complex which delivers the linear regioisomers with high selectivities. In addition, the formation of unexpected dihydroaminoalkylation products from styrenes and N-methylanilines is reported.