157286-80-1Relevant articles and documents
Synthesis and oral efficacy of a 4-(butylethylamino)pyrrolo[2,3- d]pyrimidine: A centrally active corticotropin-releasing factor1 receptor antagonist
Chen, Yuhpyng L.,Mansbach, Robert S.,Winter, Steven M.,Brooks, Elizabeth,Collins, Judith,Corman, Michael L.,Dunaiskis, Audrey R.,Faraci, W. Stephen,Gallaschun, Randall J.,Schmidt, Anne,Schulz, David W.
, p. 1749 - 1754 (1997)
The syntheses of a centrally active nonpeptide CRF1 receptor antagonist 2, butylethyl[2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3- d]pyrimidin-4-yl]amine (CP-154,526), and its analogs 11-14 and [3H]-2 are reported. The in v