157287-08-6Relevant academic research and scientific papers
N-Acyl-2-methylaziridines: Synthesis and utility in the C-acylation of β-ketoester derived dianions
Lygo, Barry
, p. 12859 - 12868 (2007/10/02)
A 'one pot' method for the preparation of N-acyl-2-methylaziridines is described, and the utility of these compounds in the C-acylation of dianions derived from β-ketoesters investigated. Application of the methodology to the synthesis of the polyketide natural product yangonin is also described.
N-acyl aziridines - C-acylating agents for the preparation of polyketides
Lygo, Barry
, p. 5073 - 5074 (2007/10/02)
A one-pot synthesis of N-acylaziridines from carboxylic acids has been developed, and their reaction with dianions derived from β-ketoesters studied. The aziridines were found to be efficient C-acylating agents, giving polyketide-like products in good ove
