1573120-93-0Relevant articles and documents
Regioselective hydroacylation of 1,3-dienes by cobalt catalysis
Chen, Qing-An,Kim, Daniel K.,Dong, Vy M.
supporting information, p. 3772 - 3775 (2014/04/03)
We describe a cobalt-catalyzed hydroacylation of 1,3-dienes with non-chelating aldehydes. Aromatic aldehydes provide 1,4-addition products as the major isomer, while aliphatic aldehydes favor 1,2-hydroacylation products. The kinetic profile supports an oxidative cyclization mechanism involving a cobaltacycle intermediate that undergoes transformation with high regio- and stereoselectivity.