1573176-65-4Relevant academic research and scientific papers
Silylethynyl substituents as porphyrin protecting groups for solubilization and selectivity control
Oda, Kazuma,Akita, Masanari,Hiroto, Satoru,Shinokubo, Hiroshi
supporting information, p. 1818 - 1821 (2014/04/17)
Silylethynyl substituents are proposed as protecting groups for porphyrin derivatives to enhance their solubility and enable regioselective functionalization. After usage as protecting groups, silylethynyl groups at the meso-positions can be efficiently removed upon heating with aqueous H 2SO4 in the presence of a surfactant. This approach was applied to the preparation of unsymmetrically β-substituted porphyrins and porphin-porphyrin oligomers, which were inaccessible by conventional methods.
