15732-28-2Relevant academic research and scientific papers
Highly efficient aminocarbonylation of iodoarenes at atmospheric pressure catalyzed by a robust acenaphthoimidazolyidene allylic palladium complex
Fang, Weiwei,Deng, Qinyue,Xu, Mizhi,Tu, Tao
supporting information, p. 3678 - 3681 (2013/08/23)
A robust allylic palladium-NHC complex was developed and exhibited extremely high catalytic activity toward aminocarbonylation of various (hetero)aryl iodides under atmospheric carbon monoxide pressure, in which a broad range of secondary and primary amines were well tolerated. In addition, the concise synthesis of an anticancer drug tamibarotene was accomplished even in a gram scale, further highlighting the practical applicability of the protocol.
REARRANGEMENT OF NITRONES TO AMIDES USING CHLOROSULFONYL ISOCYANATE
Joseph, Sajan P.,Dhar, D. N.
, p. 5979 - 5983 (2007/10/02)
Reaction of chlorosulfonyl isocyanate (CSI) with nitrones 1a-n and 5a,b has been studied. α,α,N-Triaryl nitrones 1a-n react with CSI to form the N,N-diaryl arylamides 3a-n and 4i-n in good yields.In the case of α-H,α,N-diaryl nitrones 5a,b however, two compounds viz., the rearranged product 11a,b and the 1,4-dihydro tetrazines 10a,b are formed.The effect of substituents on the rearrangement has been studied.It is found that the nature of the substituents has got a profound effect on the rearrangement.We have also noted that the rearrangement is independent of the syn or anti configurations of the nitrones.
