1573209-00-3

Upstream product

• 114971-31-2 1-phenylpropan-2-one O-acetyl oxime 
• 358621-92-8 N-(p-tolylsulfonyl)-1,3-diphenyl-2-propen-1-imine 
• 34989-82-7 3-methylbenzo[d]isothiazole-1,1-dioxide 
• 81-07-2 saccharin 
• 673-32-5 1-Phenylprop-1-yne 

Relevant academic research and scientific papers

Synthesis of Highly Substituted Pyridines through Copper-Catalyzed Condensation of Oximes and α,β-Unsaturated Imines

A copper-catalyzed condensation reaction of oxime acetates and α,β-unsaturated ketimines to give pyridine derivatives is reported. The reaction features mild conditions, high functional-group compatibility, and high regioselectivity with respect to unsymmetrical oxime acetates, thus allowing the preparation of a wide range of polysubstituted pyridines, many of which are not readily accessible by conventional condensation methods.

Highly functionalized pyridines synthesis from N-sulfonyl ketimines and alkynes using the N-S bond as an internal oxidant

The N-S bond-based internal oxidant offers a distinct approach for the synthesis of highly functionalized pyridines. A novel Rh(III)-catalyzed one-pot process undergoes an efficient C-C/C-N bond formation along with desulfonylation under very mild conditions. The method is quite simple, general, and efficient.