1574184-85-2Relevant academic research and scientific papers
Amides and Ethers as Chemoselective Surrogates for Copper(II)-Catalyzed ortho Benzoyloxylation of 2-Phenylpyridines
Yedage, Subhash L.,Bhanage, Bhalchandra M.
, p. 2161 - 2169 (2015/09/15)
Chemoselective ortho benzoyloxylation of 2-phenylpyridine derivatives using amides and ethers as novel arylcarboxy sources using a Cu(II)/TBHP catalytic system has been reported. It is a simple protocol for ortho benzoyloxylation using amides and ethers as surrogates. A broad range of amides and ethers was found to be compatible under optimized reaction conditions to provide the corresponding products in good to excellent yield. The reaction proceeds through the cleavage of C-N, C-O, and C-H bonds and the formation of a new C-O bond via C-H functionalization.
Copper catalyzed oxidative ortho-C-H benzoxylation of 2-phenylpyridines with benzyl alcohols and benzyl amines as benzoxylation sources
Khemnar, Ashok B.,Bhanage, Bhalchandra M.
, p. 9631 - 9637 (2015/02/19)
A simple and efficient protocol for the oxidative ortho benzoxylation of 2-phenylpyridines with benzyl alcohols and benzyl amines via C-H bond activation has been developed. The present protocol uses benzyl alcohol and benzyl amine as inexpensive and easi
Terminal aryl alkenes and alkynes as arylcarboxy surrogates toward o -Benzoxylation of 2-phenylpyridine catalyzed by copper
Rout, Saroj Kumar,Guin, Srimanta,Gogoi, Anupal,Majji, Ganesh,Patel, Bhisma K.
supporting information, p. 1614 - 1617 (2014/04/17)
A variety of styrenes and phenylacetylenes serve as excellent arylcarboxy sources in bringing about substrate directed o-benzoxylation of 2-phenylpyridine derivatives catalyzed by Cu(II) in the presence of TBHP. This reaction proceeds via formation of phenylglyoxal followed by decarbonylation to benzoyl radical/benzaldehyde which acts as the arylcarboxy source.
