157422-69-0 Usage
Chemical class
Pyridoindole core with various functional groups
Explanation
The compound has a pyridoindole core structure, which is a fused ring system consisting of a six-membered indole ring and a six-membered pyridine ring.
Explanation
A cyano group (CN) is present at the 8-position of the pyridoindole core, which may contribute to the compound's biological activity and solubility.
Explanation
A phenyl group (C6H5) is attached at the 3-position of the pyridoindole core, which can influence the compound's solubility, stability, and interaction with biological targets.
Explanation
The compound has an acetamide side chain with a trifluorohydroxyisopropyl group, which can affect the compound's solubility and interaction with biological targets.
Explanation
This group is present in the acetamide side chain and can influence the compound's solubility and interaction with biological targets.
Explanation
The compound's structural similarity to known biologically active substances suggests that it may have its own biological activity, making it of interest for medicinal chemistry research.
Explanation
The presence of these functional groups can affect the compound's solubility in various solvents, which is important for its potential pharmaceutical applications.
Explanation
Although the compound has potential pharmaceutical applications due to its structural features and possible biological activity, additional studies and research are needed to fully understand its properties and potential uses.
Cyano group
8-cyano
Phenyl group
3-phenyl
Acetamide side chain
2-yl)-N-(3,3,3-trifluoro-2-hydroxy-1-isopropylpropyl)acetamide
Trifluorohydroxyisopropyl group
3,3,3-trifluoro-2-hydroxy-1-isopropylpropyl
Biological activity potential
Similarity to biologically active substances
Solubility
Influenced by cyano, phenyl, trifluoro, and hydroxyisopropyl groups
Potential pharmaceutical applications
Requires further research and studies
Check Digit Verification of cas no
The CAS Registry Mumber 157422-69-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,4,2 and 2 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 157422-69:
(8*1)+(7*5)+(6*7)+(5*4)+(4*2)+(3*2)+(2*6)+(1*9)=140
140 % 10 = 0
So 157422-69-0 is a valid CAS Registry Number.
157422-69-0Relevant academic research and scientific papers
Non-peptidic Inhibitors of Human Leukocyte Elastase. 4. Design, Synthesis, and in Vitro and in Vivo Activity of a Series of β-Carbolinone-Containing Trifluoromethyl Ketones
Veale, Chris A.,Damewood, James R.,Steelman, Gary B.,Bryant, Craig,Gomes, Bruce,Williams, Joseph
, p. 86 - 97 (2007/10/02)
A novel series of human leukocyte elastase (HLE) inhibitors containing the β-carbolinone ring system are reported.The design of these trifluoromethyl ketone-based inhibitors used a combination of structural information obtained from X-ray crystallography
