157422-75-8

Upstream product

• 161488-60-4 2-(8-formyl-1-oxo-3-phenyl-1,2-dihydropyrido<3,4-b>indol-2-yl)-N-(2-hydroxy-3,3,3-trifluoro-1-isopropyl)propylacetamide 
• 157422-74-7 2-allyl-9-benzyl-8-cyano-3-phenylpyrido<3,4-b>indol-1(2H)-one 
• 1026535-74-9 1-Benzyl-2-chlorocarbonyl-1H-indole-7-carboxylic acid 
• 1026828-23-8 1-Benzyl-7-cyano-1H-indole-2-carbonyl chloride 
• 157422-71-4 1-benzyl-7-cyanoindole-2-carboxylic acid 
• 157422-73-6 N-allyl-2,2-diethoxy-1-phenylethylamine 
• 6175-45-7 2,2-diethoxyacetophenone 
• 1026969-59-4 9-Benzyl-1-oxo-2-(2-oxo-ethyl)-3-phenyl-2,9-dihydro-1H-β-carboline-8-carbonitrile 

Downstream Products

• 157422-76-9 2-(9-Benzyl-8-cyano-1-oxo-3-phenyl-1,9-dihydro-β-carbolin-2-yl)-N-(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propyl)-acetamide 
• 161488-60-4 2-(8-formyl-1-oxo-3-phenyl-1,2-dihydropyrido<3,4-b>indol-2-yl)-N-(2-hydroxy-3,3,3-trifluoro-1-isopropyl)propylacetamide 
• 157422-69-0 2-(8-cyano-1-oxo-3-phenyl-1,2-dihydropyrido<3,4-b>indol-2-yl)-N-(3,3,3-trifluoro-2-hydroxy-1-isopropylpropyl)acetamide 
• 1026600-74-7 1-Oxo-3-phenyl-2-[(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propylcarbamoyl)-methyl]-2,9-dihydro-1H-β-carboline-8-carboxylic acid 
• 1026864-34-5 2-<8-(methoxycarbonyl)-1-oxo-3-phenyl-1,2-dihydropyrido<3,4-b>indol-2-yl>-N-(3,3,3-trifluoro-2-hydroxy-1-isopropylpropyl)acetamide 
• 157422-65-6 2-(8-Methoxycarbonyl-1-oxo-3-phenyl-1,2-dihydropyrido[3,4-b]-indol-2-yl)-N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)acetamide 

Relevant academic research and scientific papers

Non-peptidic Inhibitors of Human Leukocyte Elastase. 4. Design, Synthesis, and in Vitro and in Vivo Activity of a Series of β-Carbolinone-Containing Trifluoromethyl Ketones

A novel series of human leukocyte elastase (HLE) inhibitors containing the β-carbolinone ring system are reported.The design of these trifluoromethyl ketone-based inhibitors used a combination of structural information obtained from X-ray crystallography