1574285-38-3

Upstream product

• 151103-08-1 4-difluoromethoxy-3-hydroxybenzaldehyde 
• 71118-98-4 4-hydroxy-3-isopropoxybenzaldehyde 
• 1574285-91-8 C₁₁H₁₃F₂NO₃ 
• 177429-27-5 ethyl 4-benzyloxy-3-hydroxybenzoate 
• 1574285-36-1 C₁₄H₁₅F₂NO₄ 
• 1574285-32-7 C₁₆H₁₇F₂NO₅ 
• 1574285-30-5 C₁₅H₁₇NO₅ 
• 1574285-28-1 C₂₂H₂₃NO₅ 
• 1574285-26-9 C₁₇H₁₉NO₃ 
• 159783-48-9 4-Difluoromethoxy-3-(1-methyl)ethoxybenzoic acid 
• 93652-48-3 4-benzyloxy-3-isopropoxy-benzoic acid 

Downstream Products

• 937782-05-3 N-({2-[4-(difluoromethoxy)-3-isopropoxyphenyl]oxazole-4-yl}methyl)-2-ethoxybenzamide 
• 1574285-40-7 2-((2-(4-difluoromethoxy-3-isopropoxyphenyl)oxazol-4-yl)methyl)isoindoline-1,3-dione 

Relevant academic research and scientific papers

Oxazole compound crystal

PROBLEM TO BE SOLVED: To provide a crystal of a specific oxazole compound having a specific inhibitory action on DE4, and having excellent stability. SOLUTION: The present invention relates to a crystal of an oxazole compound represented by formula (5), t

OXAZOLE COMPOUND CRYSTAL

Provided is a crystal of a specific oxazole compound that has specific inhibitory activity against PDE4, and that shows excellent stability. Specifically, provided is a crystal of an oxazole compound represented by formula (5) wherein the crystal has peak

METHOD FOR PRODUCING OXAZOLE COMPOUND

An object of the present invention is to provide a novel method for producing an oxazole compound. The invention relates to a method for producing a compound represented by formula (1): wherein R1 is lower alkyl group or halogen substituted lower alkyl group, R2 is lower alkyl group, R5 is lower alkyl group, R11 is lower alkyl group, halogen substituted lower alkyl group or a group represented by formula: -CY2COOR12, wherein Y is a halogen atom, R12 is an alkali metal atom or lower alkyl group, Ar1 is phenyl group substituted with lower alkyl group, etc., or pyridyl group substituted with lower alkyl group, etc., X2, X3 and X9 are the same or different and are halogen atoms, X4 is a leaving group, and M is an alkali metal atom.