1574828-57-1

Basic information

• Product Name: 4-(4-chlorophenyl)-2-(thiophen-3-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine
• Synonyms: 4-(4-chlorophenyl)-2-(thiophen-3-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine
• CAS NO: 1574828-57-1
• Molecular Weight: 311.835
• Mol File: 1574828-57-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-chlorophenyl)-2-(thiophen-3-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-chlorophenyl)-2-(thiophen-3-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine(1574828-57-1)
• EPA Substance Registry System: 4-(4-chlorophenyl)-2-(thiophen-3-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine(1574828-57-1)

Safety Data

• Hazardous Substances Data: 1574828-57-1(Hazardous Substances Data)

Upstream product

• 1574828-48-0 2-(1-(4-chlorophenyl)-3-oxo-3-(thiophen-3-yl)propyl)cyclopentanone 
• 144080-41-1 3-(4-chlorophenyl)-1-(thiophen-3-yl)prop-2-en-1-one 
• 120-92-3 cyclopentanone 

Relevant articles and documents

Synthesis and characterization of some novel multisubstituted 6,7-Dihydro-5 H -cyclopenta[ b ]pyridine derivatives

In this study, we describe systematic preparation of a series of aryl-substituted pyridine derivatives. The 1,5-dicarbonyls (3a-i) were prepared in the solvent-free conditions starting from chalcone derivatives (1a-i). The target compounds, 4-aryl-2-(thiophen-3-yl)-6,7-dihydro-5H-cyclopenta[b]-pyridine derivatives (5a-i), were synthesized by a cyclization reaction of the 1,5-dicarbonyls (3a-i) with ammonium acetate (NH4OAc) in acetic acid. The characterization of synthesized compounds was proved by elemental analyses, infrared, mass spectrometry, and 1H and 13C NMR spectroscopy. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications for the following free supplemental resource(s): Full experimental and spectral details.]