157488-91-0Relevant academic research and scientific papers
Mono- and Di-Fucosylated Glycans of the Parasitic Worm S. mansoni are Recognized Differently by the Innate Immune Receptor DC-SIGN
Srivastava, Apoorva D.,Unione, Luca,Wolfert, Margreet A.,Valverde, Pablo,Ardá, Ana,Jiménez-Barbero, Jesús,Boons, Geert-Jan
, p. 15605 - 15612 (2020)
The parasitic worm, Schistosoma mansoni, expresses unusual fucosylated glycans in a stage-dependent manner that can be recognized by the human innate immune receptor DC-SIGN, thereby shaping host immune responses. We have developed a synthetic approach fo
Synthesis of Neisseria meningitidis X capsular polysaccharide fragments
Morelli, Laura,Lay, Luigi
, p. 166 - 184 (2013/01/16)
Serotype X of Neisseria meningitidis bacterium (Men X) recently emerged as a substantial threat to public health. Since anti-meningococcal vaccines currently available or under investigation do not contain antigenic components of Men X capsular polysaccha
Synthesis of monomeric and dimeric repeating units of the zwitterionic type 1 capsular polysaccharide from Streptococcus pneumoniae
Wu, Xiangyang,Cui, Lina,Lipinski, Tomasz,Bundle, David R.
scheme or table, p. 3476 - 3488 (2010/07/04)
Zwitterionic polysaccharides (ZPSs) from Bacteroides fragilis and Streptococcus pneumoniae display unique T-cell activities. The first synthesis of a hexasaccharide representing two repeating units of the zwitterionic capsular polysaccharide from S. pneum
Modular synthesis of heparan sulfate oligosaccharides for structure-activity relationship studies
Arungundram, Sailaja,Al-Mafraji, Kanar,Asong, Jinkeng,Leach III, Franklin E.,Amster, I. Jonathan,Venot, Andre,Turnbull, Jeremy E.,Boons, Geert-Jan
scheme or table, p. 17394 - 17405 (2010/03/23)
Although hundreds of heparan sulfate binding proteins have been identified and implicated in a myriad of physiological and pathological processes, very little information is known about the ligand requirements for binding and mediating biological activiti
Efficient synthesis of lactoneo series antigen Lewis Y (Ley)
Hummel,Schmidt
, p. 941 - 954 (2007/10/03)
The synthesis of glycosphingolipid Lewis Y (1) could be efficiently carried out, based on the connection of building blocks 2-7. Reaction of fucosyl donor 2 with azidoglucose derivative 4 as acceptor gave α(1-3)-linked disaccharide 8, which was transforme
Glycosyl Phosphites as Glycosyl Donors - A Comparative Study
Mueller, Thomas,Hummel, Gerd,Schmidt, Richard R.
, p. 325 - 330 (2007/10/02)
Tri-O-benzyl-L-fucose (3) was transformed into the bis(trichloroethyl) phosphite derivative 4 which was allowed to react with 3-O-unprotected azidoglucose 7 as fucosyl acceptor in the presence of TMSOTf as catalyst to furnish disaccharide building block 1
